Evidence map›Paper›PMID 29378352›Full record

ArticleThrombosis and haemostasis2018

Atherothrombosis and Thromboembolism: Position Paper from the Second Maastricht Consensus Conference on Thrombosis.

H M H Spronk, T Padro, J E Siland, J H Prochaska, J Winters, A C van der Wal, J J Posthuma, G Lowe, E d'Alessandro, P Wenzel and 53 more

Open access · bronzeAbstract readConference ProceedingsConsensus Statement
In one paragraph

Article in Thrombosis and haemostasis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 58 citations in OpenAlex.

  1. Review
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  11. PAR-4/CaCardiovascular diabetology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

63 authors at 20 institutions in 9 countries.

H M H SpronkLaboratory for Clinical Thrombosis and Haemostasis, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht, The Netherlands.
T PadroCardiovascular Research Center (ICCC), Hospital Sant Pau, Barcelona, Spain.
J E SilandDepartment of Cardiology, University Medical Center Groningen, Groningen, The Netherlands.
J H ProchaskaCenter for Cardiology/Center for Thrombosis and Hemostasis/DZHK, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
J WintersDepartment of Physiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
A C van der WalDepartment of Pathology, Academic Medical Center (AMC), Amsterdam, The Netherlands.
J J PosthumaLaboratory for Clinical Thrombosis and Haemostasis, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht, The Netherlands.
G LoweInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland.
E d'AlessandroDepartment of Physiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
P WenzelDepartment of Cardiology, Universitätsmedizin Mainz, Mainz, Germany.
D M CoenenDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
P H ReitsmaEinthoven Laboratory, Leiden University Medical Center, Leiden, The Netherlands.
W RufCenter for Cardiology/Center for Thrombosis and Hemostasis/DZHK, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
R H van GorpDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
R R KoenenDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
T VajenDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
N A AlshaikhDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
A S WolbergDepartment of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, North Carolina, United States.
F L MacraeThrombosis and Tissue Repair Group, Division of Cardiovascular and Diabetes Research, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, UK.
N AsquithThrombosis and Tissue Repair Group, Division of Cardiovascular and Diabetes Research, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, UK.
J HeemskerkDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
A HeinzmannDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
M MoorlagSynapse, Maastricht, The Netherlands.
N MackmanDepartment of Medicine, UNC McAllister Heart Institute, University of North Carolina, Chapel Hill, North Carolina, United States.
P van der MeijdenDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
J C M MeijersDepartment of Plasma Proteins, Sanquin, Amsterdam, The Netherlands.
M HeestermansEinthoven Laboratory, Leiden University Medical Center, Leiden, The Netherlands.
T RennéDepartment of Molecular Medicine and Surgery, Karolinska Institutet and University Hospital, Stockholm, Sweden.
S DóllemanDepartment of Nephrology, Leiden University Medical Centre, Leiden, The Netherlands.
W ChayouâSynapse, Maastricht, The Netherlands.
R A S AriënsThrombosis and Tissue Repair Group, Division of Cardiovascular and Diabetes Research, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, UK.
C C BaatenDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
M NagyDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
A KuliopulosTufts University School of Graduate Biomedical Sciences, Biochemistry/Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, Massachusetts.
J J PosmaLaboratory for Clinical Thrombosis and Haemostasis, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht, The Netherlands.
P HarrisonInstitute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom.
M J VriesLaboratory for Clinical Thrombosis and Haemostasis, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht, The Netherlands.
H J G M CrijnsDepartment of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht, The Netherlands.
E A M P DudinkDepartment of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht, The Netherlands.
H R BullerDepartment of Vascular Medicine, Academic Medical Center (AMC), Amsterdam, The Netherlands.
Y M C HenskensLaboratory for Clinical Thrombosis and Haemostasis, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht, The Netherlands.
A SjälanderDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
S ZwavelingLaboratory for Clinical Thrombosis and Haemostasis, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht, The Netherlands.
O ErkünerDepartment of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht, The Netherlands.
J W EikelboomDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
A GulpenLaboratory for Clinical Thrombosis and Haemostasis, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht, The Netherlands.
F E C M PeetersDepartment of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht, The Netherlands.
J DouxfilsDepartment of Pharmacy, Thrombosis and Hemostasis Center, Faculty of Medicine, Namur University, Namur, Belgium.
R H OlieLaboratory for Clinical Thrombosis and Haemostasis, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht, The Netherlands.
T BaglinDepartment of Haematology, Addenbrookes Hospital Cambridge, Cambridge, United Kingdom.
A LeaderLaboratory for Clinical Thrombosis and Haemostasis, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht, The Netherlands.
U SchottenCenter for Cardiology/Center for Thrombosis and Hemostasis/DZHK, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
B ScafLaboratory for Clinical Thrombosis and Haemostasis, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht, The Netherlands.
H M M van BeusekomDepartment of Experimental Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands.
L O MosnierDepartment of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, United States.
L van der VormSynapse, Maastricht, The Netherlands.
P DeclerckDepartment of Pharmaceutical and Pharmacological Sciences, University of Leuven, Leuven, Belgium.
M VisserBayer AG, Wuppertal, Germany.
D W J DippelDepartment of Neurology, Erasmus MC, Rotterdam, The Netherlands.
V J StrijbisSynapse, Maastricht, The Netherlands.
K PertiwiDepartment of Cardiovascular Pathology, University of Amsterdam, Academic Medical Center, Amsterdam, The Netherlands.
A J Ten Cate-HoekLaboratory for Clinical Thrombosis and Haemostasis, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht, The Netherlands.
H Ten CateLaboratory for Clinical Thrombosis and Haemostasis, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht, The Netherlands.
Maastricht University · NLJohannes Gutenberg University Mainz · DESynapse (Netherlands) · NLUniversity of Leeds · GBUniversity of Namur · BEAcademic Medical Center · NLLeiden University Medical Center · NLUniversity of North Carolina at Chapel Hill · USAddenbrooke's Hospital · GBBayer (Germany) · DEErasmus MC · NLErasmus University Rotterdam · NLHospital de Sant Pau · ESKarolinska University Hospital · SEKU Leuven · BELeiden University · NLMcMaster University · CARabin Medical Center · ILSanquin · NLScripps Research Institute · US

Funding

TRIP-PCI: PAR1 Pepducin-Based Interventions in Arterial ThrombosisP50HL110789 · NHLBI · TUFTS MEDICAL CENTER · PI KULIOPULOS, ATHAN · 2012 to 2016
$10.0M
Regulation of Protein C PathwaysR01HL142975 · NHLBI · SCRIPPS RESEARCH INSTITUTE, THE · PI GRIFFIN, JOHN H, MOSNIER, LAURENT OLIVIER · 2018 to 2025
$7.3M
Structure-function of cytoprotective coagulation proteases and their receptorsR01HL104165 · NHLBI · SCRIPPS RESEARCH INSTITUTE, THE · PI MOSNIER, LAURENT OLIVIER · 2011 to 2024
$6.1M
Fibrinogen and Factor XIII in Venous ThrombosisR01HL126974 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Alisa S. Wolberg · 2016 to 2026
$4.4M
Matrix Metalloprotease-PAR1 Regulation of AtherosclerosisR01HL136485 · NHLBI · TUFTS MEDICAL CENTER · PI KULIOPULOS, ATHAN · 2018 to 2021
$2.8M
British Heart Foundation FS/15/37/31513British Heart Foundation RG/13/3/30104NHLBI NIH HHS P50 HL110789NHLBI NIH HHS R01 HL104165NHLBI NIH HHS R01 HL126974NHLBI NIH HHS R01 HL136485NHLBI NIH HHS R01 HL142975
6 · The paper itself

Abstract

Atherothrombosis is a leading cause of cardiovascular mortality and long-term morbidity. Platelets and coagulation proteases, interacting with circulating cells and in different vascular beds, modify several complex pathologies including atherosclerosis. In the second Maastricht Consensus Conference on Thrombosis, this theme was addressed by diverse scientists from bench to bedside. All presentations were discussed with audience members and the results of these discussions were incorporated in the final document that presents a state-of-the-art reflection of expert opinions and consensus recommendations regarding the following five topics: 1.

Indexed as

AnticoagulantsBiomarkersBlood CoagulationErythrocytesFactor VIIIFactor XIIFactor XIIIHumansMacrophagesNetherlandsPhenotypePlaque, AtheroscleroticPolyphosphatesRisk FactorsSignal TransductionThromboembolismAnticoagulantsBiomarkersF8 protein, humanFactor VIIIFactor XIIFactor XIIIPolyphosphates

Identifiers

PMID29378352
PMCPMC6193488
OpenAlexW2785490330

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.