ReviewNeuroscience letters2019
Deconstructing arousal into wakeful, autonomic and affective varieties.
Review in Neuroscience letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 2 syntheses or guidelines pooled it, 110 citations in OpenAlex.
- Arousal and attentional processes in the relationship between pain and time perception: Evidence from a systematic review and meta-analytic structural equation modeling.Attention, perception & psychophysics · 2026Pooled it
- Evidence for domain-general arousal from semantic and neuroimaging meta-analyses reconciles opposing views on arousal.Proceedings of the National Academy of Sciences of the United States of America · 2025Pooled it
- Neurophysiological contributors to advantageous risk-taking: an experimental psychopharmacological investigation.Social cognitive and affective neuroscience · 2021Trial
- Distinct Brain Systems Support Afferent and Efferent Autonomic Activity.bioRxiv : the preprint server for biology · 2026Article
- Time to think of love, leisure, terror, and despair: emotional imagery affects temporal cognition.Psychological research · 2026Article
- Map-like representations of emotion knowledge in hippocampal-prefrontal systems.Nature communications · 2026Article
- Distinct brain systems support afferent and efferent autonomic activity.Social cognitive and affective neuroscience · 2026Article
- Relationships between brain functional connectivity and resting cardiac autonomic profiles in functional neurological disorder: A pilot study.NeuroImage. Clinical · 2026Article
- Temporally Continuous Automated Sleep-Wake Classification Using Deep Learning.medRxiv : the preprint server for health sciences · 2025Article
- Neural Sensitivity to the Heartbeat Is Modulated by Fluctuations in Affective Arousal during Spontaneous Thought.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Cortical and subcortical mapping of the human allostatic-interoceptive system using 7 Tesla fMRI.Nature neuroscience · 2025Article
- Sleep and Stroke-An Overlooked Bidirectional Influence: Why Should Sleep and Vascular Neurologists Work Closer?Journal of clinical medicine · 2025Article
- A neurofunctional signature of affective arousal generalizes across valence domains and distinguishes subjective experience from autonomic reactivity.Nature communications · 2025Article
- Neural sensitivity to the heartbeat is modulated by fluctuations in affective arousal during spontaneous thought.bioRxiv : the preprint server for biology · 2025Article
- Measuring Arousal: Promises and Pitfalls.Affective science · 2025Review
- Dynamic brain connectivity predicts emotional arousal during naturalistic movie-watching.PLoS computational biology · 2025Article
- The neural activity of auditory conscious perception.NeuroImage · 2025Article
- Cortical and subcortical mapping of the allostatic-interoceptive system in the human brain using 7 Tesla fMRI.bioRxiv : the preprint server for biology · 2025Article
- Advances in the fMRI analysis of the default mode network: a review.Brain structure & function · 2024Review
- Neural Predictors of Fear Depend on the Situation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
Arousal plays a central role in a wide variety of phenomena, including wakefulness, autonomic function, affect and emotion. Despite its importance, it remains unclear as to how the neural mechanisms for arousal are organized across them. In this article, we review neuroscience findings for three of the most common origins of arousal: wakeful arousal, autonomic arousal, and affective arousal. Our review makes two overarching points. First, research conducted primarily in non-human animals underscores the importance of several subcortical nuclei that contribute to various sources of arousal, motivating the need for an integrative framework. Thus, we outline an integrative neural reference space as a key first step in developing a more systematic understanding of central nervous system contributions to arousal. Second, there is a translational gap between research on non-human animals, which emphasizes subcortical nuclei, and research on humans using non-invasive neuroimaging techniques, which focuses more on gross anatomical characterizations of cortical (e.g. network architectures including the default mode network) and subcortical structures. We forecast the importance of high-field neuroimaging in bridging this gap to examine how the various networks within the neural reference space for arousal operate across varieties of arousal-related phenomena.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.