Evidence map›Paper›PMID 29378291›Full record

ArticleBehavioural brain research2018

Glutamine/glutamate (Glx) concentration in prefrontal cortex predicts reversal learning performance in the marmoset.

Agnès Lacreuse, Constance M Moore, Matthew LaClair, Laurellee Payne, Jean A King

Open access · greenAbstract read
In one paragraph

Article in Behavioural brain research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Agnès LacreusePsychological and Brain Sciences, University of Massachusetts, Amherst, MA 01003, United States; Neuroscience and Behavior Program, University of Massachusetts, Amherst, MA 01003, United States. Electronic address: alacreuse@psych.umass.edu.
Constance M MooreCenter for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01604, United States.
Matthew LaClairNeuroscience and Behavior Program, University of Massachusetts, Amherst, MA 01003, United States.
Laurellee PayneCenter for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01604, United States.
Jean A KingCenter for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01604, United States.
University of Massachusetts Chan Medical School · USUniversity of Massachusetts Amherst · US

Funding

Sex differences in cognitive and brain aging: a primate modelR01AG046266 · NIA · UNIVERSITY OF MASSACHUSETTS AMHERST · PI LACREUSE, AGNES · 2014 to 2018
$2.1M
4.7T Magnet System UpgradeS10OD018132 · OD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KING, JEAN A · 2014 to 2014
$598k
NIA NIH HHS R01 AG046266NIH HHS S10 OD018132
6 · The paper itself

Abstract

This study used Magnetic Resonance Spectroscopy (MRS) to identify potential neurometabolitic markers of cognitive performance in male (n = 7) and female (n = 8) middle-aged (∼5 years old) common marmosets (Callithrix jacchus). Anesthetized marmosets were scanned with a 4.7 T/40 cm horizontal magnet equipped with 450 mT/m magnetic field gradients and a 20 G/cm magnetic field gradient insert, within 3 months of completing the CANTAB serial Reversal Learning task. Neurometabolite concentrations of N-Acetyl Asparate, Myo-Inositol, Choline, Phosphocreatine + creatine, Glutamate and Glutamine were acquired from a 3 mm

Indexed as

AnimalsCallithrixFemaleGlutamic AcidGlutamineMagnetic Resonance SpectroscopyMaleNeuropsychological TestsPrefrontal CortexReversal LearningSex CharacteristicsGlutamic AcidGlutamineCognitionMagnetic resonance spectroscopyMonkeyPrimateSex differences

Identifiers

PMID29378291
PMCPMC5860997
OpenAlexW2789799959

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.