Evidence map›Paper›PMID 29377897›Full record

ArticlePloS one2018

The Camden & Islington Research Database: Using electronic mental health records for research.

Nomi Werbeloff, David P J Osborn, Rashmi Patel, Matthew Taylor, Robert Stewart, Matthew Broadbent, Joseph F Hayes

Abstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nomi WerbeloffUCL Division of Psychiatry, University College London, London, United Kingdom.ORCID 0000-0002-5485-615X
David P J OsbornUCL Division of Psychiatry, University College London, London, United Kingdom.
Rashmi PatelInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Matthew TaylorInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Robert StewartInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Matthew BroadbentSouth London and Maudsley NHS Foundation Trust, London, United Kingdom.
Joseph F HayesUCL Division of Psychiatry, University College London, London, United Kingdom.

Funding

Medical Research Council MC_PC_17214Medical Research Council MR/K002813/1Medical Research Council MR/K021362/1Medical Research Council MR/S003118/1Wellcome Trust
6 · The paper itself

Abstract

backgroundElectronic health records (EHRs) are widely used in mental health services. Case registers using EHRs from secondary mental healthcare have the potential to deliver large-scale projects evaluating mental health outcomes in real-world clinical populations.

methodsWe describe the Camden and Islington NHS Foundation Trust (C&I) Research Database which uses the Clinical Record Interactive Search (CRIS) tool to extract and de-identify routinely collected clinical information from a large UK provider of secondary mental healthcare, and demonstrate its capabilities to answer a clinical research question regarding time to diagnosis and treatment of bipolar disorder.

resultsThe C&I Research Database contains records from 108,168 mental health patients, of which 23,538 were receiving active care. The characteristics of the patient population are compared to those of the catchment area, of London, and of England as a whole. The median time to diagnosis of bipolar disorder was 76 days (interquartile range: 17-391) and median time to treatment was 37 days (interquartile range: 5-194). Compulsory admission under the UK Mental Health Act was associated with shorter intervals to diagnosis and treatment. Prior diagnoses of other psychiatric disorders were associated with longer intervals to diagnosis, though prior diagnoses of schizophrenia and related disorders were associated with decreased time to treatment.

conclusionsThe CRIS tool, developed by the South London and Maudsley NHS Foundation Trust (SLaM) Biomedical Research Centre (BRC), functioned very well at C&I. It is reassuring that data from different organizations deliver similar results, and that applications developed in one Trust can then be successfully deployed in another. The information can be retrieved in a quicker and more efficient fashion than more traditional methods of health research. The findings support the secondary use of EHRs for large-scale mental health research in naturalistic samples and settings investigated across large, diverse geographical areas.

Indexed as

AdolescentAdultAgedAged, 80 and overBiomedical ResearchCohort StudiesDatabases, FactualElectronic Health RecordsFemaleFoundationsHospitalizationHumansLondonMaleMental DisordersMental Health

Identifiers

PMID29377897
PMCPMC5788349

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.