ArticlePLoS genetics2018
WRKY23 is a component of the transcriptional network mediating auxin feedback on PIN polarity.
Article in PLoS genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 103 citations in OpenAlex.
- Article
- Dedifferentiation of Plant Cells: A Term Covering Multiple Pathways?Plants (Basel, Switzerland) · 2026Article
- Auxin Biosynthesis, Transport, Signaling, and Its Roles in Plant Leaf Morphogenesis.Plants (Basel, Switzerland) · 2025Review
- Elucidating Continental-Wide Phylogeographic and Adaptive Processes Shaping the Genome-Wide Diversity of North America's Most Widely Distributed Tree.Molecular ecology · 2025Article
- Mechanisms of auxin action in plant growth and development.Nature reviews. Molecular cell biology · 2025Review
- Genome-Wide identification and expression profiles of the WRKY transcription factor family in Artocarpus nanchuanensis.BMC plant biology · 2025Article
- Transcriptomic profiles reveal hormonal regulation of sugar-induced stolon initiation in potato.Scientific reports · 2025Article
- Damage activates EXG1 and RLP44 to suppress vascular differentiation during regeneration in Arabidopsis.Plant communications · 2025Article
- Genome-wide identiffcation of the WRKY gene family in poplar and the positive role of PsnWRKY95 in response to cadmium stress.PloS one · 2025Article
- Historical and mechanistic perspective on ABP1-TMK1-mediated cell surface auxin signaling.NPJ science of plants · 2025Review
- Article
- GmHXK2 promotes the salt tolerance of soybean seedlings by mediating AsA synthesis, and auxin synthesis and distribution.BMC plant biology · 2024Article
- Elucidating the callus-to-shoot-forming mechanism in Capsicum annuum 'Dempsey' through comparative transcriptome analyses.BMC plant biology · 2024Article
- Auxin efflux carrier PsPIN4 identified through genome-wide analysis as vital factor of petal abscission.Frontiers in plant science · 2024Article
- Transcriptional activation by WRKY23 and derepression by removal of bHLH041 coordinately establish callus pluripotency in Arabidopsis regeneration.The Plant cell · 2023Article
- A Common Molecular Signature Indicates the Pre-Meristematic State of Plant Calli.International journal of molecular sciences · 2023Review
- Fourteen Stations of Auxin.Cold Spring Harbor perspectives in biology · 2022Review
- The Phytotoxin Myrigalone A Triggers a Phased Detoxification Programme and InhibitsInternational journal of molecular sciences · 2022Article
- Auxin analog-induced Ca2+ signaling is independent of inhibition of endosomal aggregation in Arabidopsis roots.Journal of experimental botany · 2022Article
- Two phylogenetically unrelated peptide-receptor modules jointly regulate lateral root initiation via a partially shared signaling pathway in Arabidopsis thaliana.The New phytologist · 2022Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Auxin is unique among plant hormones due to its directional transport that is mediated by the polarly distributed PIN auxin transporters at the plasma membrane. The canalization hypothesis proposes that the auxin feedback on its polar flow is a crucial, plant-specific mechanism mediating multiple self-organizing developmental processes. Here, we used the auxin effect on the PIN polar localization in Arabidopsis thaliana roots as a proxy for the auxin feedback on the PIN polarity during canalization. We performed microarray experiments to find regulators of this process that act downstream of auxin. We identified genes that were transcriptionally regulated by auxin in an AXR3/IAA17- and ARF7/ARF19-dependent manner. Besides the known components of the PIN polarity, such as PID and PIP5K kinases, a number of potential new regulators were detected, among which the WRKY23 transcription factor, which was characterized in more detail. Gain- and loss-of-function mutants confirmed a role for WRKY23 in mediating the auxin effect on the PIN polarity. Accordingly, processes requiring auxin-mediated PIN polarity rearrangements, such as vascular tissue development during leaf venation, showed a higher WRKY23 expression and required the WRKY23 activity. Our results provide initial insights into the auxin transcriptional network acting upstream of PIN polarization and, potentially, canalization-mediated plant development.
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