ArticlePlant biotechnology journal2018
WRKY1 acts as a key component improving resistance against Alternaria solani in wild tomato, Solanum arcanum Peralta.
Article in Plant biotechnology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 52 citations in OpenAlex.
- Root colonization by Serendipita indica triggers resistance against stem rot in Arachis hypogaea L.World journal of microbiology & biotechnology · 2025Article
- Reactive oxygen species production and signal transduction in response to stress triggered by Alternaria elicitors in Brassicaceae.Plant molecular biology · 2025Review
- The Combination of α-FeJournal of basic microbiology · 2025Article
- Transcriptome analyses revealPhysiology and molecular biology of plants : an international journal of functional plant biology · 2025Article
- Colonization of Serendipita indica enhances resistance against Phoma arachidicola in Arachis hypogaea L.World journal of microbiology & biotechnology · 2025Article
- Comparative proteomic and metabolomic analyses reveal resistance mechanisms in Chilli pepper roots of resistant and susceptible varieties toFrontiers in plant science · 2025Article
- Transcriptome responses of Arabidopsis to necrotrophic fungus Alternaria brassicae reveal pathways and candidate genes associated with resistance.Plant molecular biology · 2024Article
- Advances in the Research on Plant WRKY Transcription Factors Responsive to External Stresses.Current issues in molecular biology · 2023Review
- Green Synthesized Silver Nanoparticles: A Novel Approach for the Enhanced Growth and Yield of Tomato against Early Blight Disease.Microorganisms · 2023Article
- Contrasting Roles of Ethylene Response Factors in Pathogen Response and Ripening in Fleshy Fruit.Cells · 2022Review
- AUXIN RESPONSE FACTOR 16 (StARF16) regulates defense gene StNPR1 upon infection with necrotrophic pathogen in potato.Plant molecular biology · 2022Article
- Essential oil from Lavandula angustifolia elicits expression of three SbWRKY transcription factors and defense-related genes against sorghum damping-off.Scientific reports · 2022Article
- Physiological and transcriptome profiling revealed defense networks duringFrontiers in plant science · 2022Article
- Review: Holistic pest management against early blight disease towards sustainable agriculture.Pest management science · 2021Review
- Computational analysis of microarray data of Arabidopsis thaliana challenged with Alternaria brassicicola for identification of key genes in Brassica.Journal, genetic engineering & biotechnology · 2020Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early blight (EB), caused by Alternaria solani, is a major threat to global tomato production. In comparison with cultivated tomato (Solanum lycopersicum), a wild relative, S. arcanum exhibits strong resistance against EB. However, molecular cascades operating during EB resistance in wild or cultivated tomato plants are largely obscure. Here, we provide novel insight into spatio-temporal molecular events in S. arcanum against A. solani. Transcriptome and co-expression analysis presented 33-WRKYs as promising candidates of which 12 SaWRKYs displayed differential expression patterns in resistant and susceptible accessions during EB disease progression. Among these, SaWRKY1 exhibited induced expression with significant modulation in xyloglucan endotrans hydrolase 5 (XTH5) and MYB2 expressions that correlated with the disease phenotypes. Electro-mobility shift assay confirmed physical interaction of recombinant SaWRKY1 to SaXTH5 and SaMYB2 promoters. Comparative WRKY1 promoter analysis between resistant and susceptible plants revealed the presence of crucial motifs for defence mechanism exclusively in resistant accession. Additionally, many defence-related genes displayed significant expression variations in both the accessions. Further, WRKY1 overexpressing transgenic plants exhibited higher levels of EB resistance while RNAi silencing lines had increased susceptibility to A. solani with altered expression of XTH5 and MYB2. Overall, these findings demonstrate the positive influence of WRKY1 in improving EB resistance in wild tomato and this could be further utilized as a potential target through genetic engineering to augment protection against A. solani in crop plants.
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