Evidence map›Paper›PMID 29377444›Full record

ArticleStem cells (Dayton, Ohio)2018

An Induced Pluripotent Stem Cell Patient Specific Model of Complement Factor H (Y402H) Polymorphism Displays Characteristic Features of Age-Related Macular Degeneration and Indicates a Beneficial Role for UV Light Exposure.

Graham Anderson, Pierre Bagnaninchi, Andrew McLeod, Baljean Dhillon

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Stem cells (Dayton, Ohio), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Graham AndersonUniversity of Edinburgh College of Medicine and Veterinary Medicine - MRC Centre for Regenerative Medicine, Edinburgh, United Kingdom.ORCID 0000-0002-6252-9570
Pierre BagnaninchiUniversity of Edinburgh College of Medicine and Veterinary Medicine - MRC Centre for Regenerative Medicine, Edinburgh, United Kingdom.
Andrew McLeodUniversity of Edinburgh School of GeoSciences, Edinburgh, United Kingdom.
Baljean DhillonUniversity of Edinburgh College of Medicine and Veterinary Medicine - Centre for Clinical Brain Sciences, Edinburgh, United Kingdom NHS Lothian - Clinical Opthalmology, Edinburgh, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Macular DegenerationModels, BiologicalPolymorphism, GeneticUltraviolet RaysComplement Factor HHumansInduced Pluripotent Stem CellsCFH protein, humanComplement Factor HAMDiPSRPEUV Exposure

Identifiers

PMID29377444

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.