ArticleJournal of veterinary internal medicine2018
Evaluation of Serum Symmetric Dimethylarginine Concentration as a Marker for Masked Chronic Kidney Disease in Cats With Hyperthyroidism.
Article in Journal of veterinary internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 54 citations in OpenAlex.
- Longitudinal evaluation of discordant symmetric dimethylarginine and creatinine as markers of glomerular filtration rate in radioiodine-treated hyperthyroid cats.Journal of feline medicine and surgery · 2026Article
- Changes in serum symmetric dimethylarginine concentrations after treatment of feline hyperthyroidism with antithyroid medications.Journal of feline medicine and surgery · 2026Article
- Effect of Presence of Uni- or Bilateral Thyroid Adenoma on Recovery of Pituitary-Thyroid Axis and Creatinine Concentration in Radioiodine-Treated Cats.Animals : an open access journal from MDPI · 2024Article
- Untargeted metabolomic profiling of serum from client-owned cats with early and late-stage chronic kidney disease.Scientific reports · 2024Article
- Changes in symmetric dimethylarginine and glomerular filtration rates in hyperthyroid cats undergoing radioiodine therapy.Journal of feline medicine and surgery · 2023Article
- Radioactive iodine dose and survival in cats with hyperthyroidism (2015-2020).Journal of feline medicine and surgery · 2022Article
- Evaluation of symmetric dimethylarginine in cats with acute kidney injury and chronic kidney disease.Journal of veterinary internal medicine · 2022Article
- Hyperthyroid cats and their kidneys: a literature review.Australian veterinary journal · 2022Review
- Radioiodine treatment of hyperthyroidism in cats: results of 165 cats treated by an individualised dosing algorithm in Spain.Journal of feline medicine and surgery · 2022Article
- Management of Feline Hyperthyroidism and the Need to Prevent Oxidative Stress: What Can We Learn from Human Research?Antioxidants (Basel, Switzerland) · 2021Review
- A dosing algorithm for individualized radioiodine treatment of cats with hyperthyroidism.Journal of veterinary internal medicine · 2021Article
- Liver-type fatty acid-binding protein and neutrophil gelatinase-associated lipocalin in cats with chronic kidney disease and hyperthyroidism.Journal of veterinary internal medicine · 2021Article
- Assessment of treatment outcomes in hyperthyroid cats treated with an orally administered fixed dose of radioiodine.Journal of feline medicine and surgery · 2020Article
- Assessment of serum symmetric dimethylarginine and creatinine concentrations in hyperthyroid cats before and after a fixed dose of orally administered radioiodine.Journal of veterinary internal medicine · 2020Article
- Symmetric dimethylarginine in hyperthyroid cats before and after treatment with radioactive iodine.Journal of feline medicine and surgery · 2020Article
- Cardiovascular-renal axis disorder and acute-phase proteins in cats with congestive heart failure caused by primary cardiomyopathy.Journal of veterinary internal medicine · 2020Article
- Hyperthyroidism is not a risk factor for subclinical bacteriuria in cats: A prospective cohort study.Journal of veterinary internal medicine · 2020Article
- Prevalence of iatrogenic hypothyroidism in hyperthyroid cats treated with radioiodine using an individualised scoring system.Journal of feline medicine and surgery · 2019Article
- Assessment of symmetric dimethylarginine as a biomarker of renal function in hyperthyroid cats treated with radioiodine.Journal of veterinary internal medicine · 2019Article
- Changes in thyroid and renal function after bilateral thyroidectomy in cats.Journal of veterinary internal medicine · 2019Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHyperthyroidism can complicate (mask) the diagnosis of chronic kidney disease (CKD) because it increases glomerular filtration rate and decreases body muscle mass, both of which can lower serum creatinine concentrations. Currently, there is no clinical test that can reliably predict which hyperthyroid cats have concurrent azotemic CKD that will become apparent after treatment of the hyperthyroidism.
objectivesTo investigate serum symmetric dimethylarginine (SDMA) concentration as a potential marker of masked azotemia in untreated hyperthyroid cats. ANIMALS: Two hundred and sixty-two hyperthyroid cats and 206 aged-matched, clinically normal cats.
methodsProspective study. We measured creatinine, urea nitrogen, SDMA, T
resultsNo hyperthyroid cats were azotemic before treatment, but 42 (16%) became azotemic when rechecked at 4-8 months (median, 6 months) after CONCLUSIONS AND CLINICAL IMPORTANCE: Finding a high serum SDMA concentration in a hyperthyroid cat can help predict development of azotemia after treatment. The test has high diagnostic test specificity (few false-positive results) but relatively low sensitivity (fails to predict azotemia in most hyperthyroid cats).
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