ReviewThe Journal of physiology2018
Role of the carotid body chemoreceptors in glucose homeostasis and thermoregulation in humans.
Review in The Journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 38 citations in OpenAlex.
- Pioglitazone does not enhance exogenous glucose oxidation or metabolic clearance rate during aerobic exercise in men under acute high-altitude exposure.American journal of physiology. Regulatory, integrative and comparative physiology · 2024Trial
- Role of the carotid chemoreceptors in insulin-mediated sympathoexcitation in humans.American journal of physiology. Regulatory, integrative and comparative physiology · 2020Trial
- The carotid body in sepsis: From homeostatic defense to immunometabolic dysregulation.Brain, behavior, & immunity - health · 2026Review
- Pathological respiratory chemoreflex activation predicts improvement of neurocognitive function in response to continuous positive airway pressure therapy.Frontiers in neuroscience · 2025Article
- Cluster Headache and Hypoxia: Breathing New Life into an Old Theory, with Novel Implications.Neurology international · 2024Review
- Reductive stress in mitochondria isolated from the carotid body of type 1 diabetic male Wistar rats.Physiological reports · 2024Article
- K252a Prevents Microglial Activation Induced by Anoxic Stimulation of Carotid Bodies in Rats.Toxics · 2023Article
- Acute effects of insulin and insulin-induced hypoglycaemia on carotid body chemoreceptor activity and cardiorespiratory responses in dogs.Experimental physiology · 2023Article
- Brain Glucose Sensing and the Problem of Relative Hypoglycemia.Diabetes care · 2023Review
- Obstructive sleep apnoea-related respiratory events and desaturation severity are associated with the cardiac response.ERJ open research · 2022Article
- Role of the Autonomic Nervous System in the Hemodynamic Response to Hyperinsulinemia-Implications for Obesity and Insulin Resistance.Current diabetes reports · 2022Review
- Human Cerebral Perfusion, Oxygen Consumption, and Lactate Production in Response to Hypoxic Exposure.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- GLP1R Attenuates Sympathetic Response to High Glucose via Carotid Body Inhibition.Circulation research · 2022Article
- Chemoreflex Control as the Cornerstone in Immersion Water Sports: Possible Role on Breath-Hold.Frontiers in physiology · 2022Review
- The carotid body: A novel key player in neuroimmune interactions.Frontiers in immunology · 2022Review
- Longer apneas and hypopneas are associated with greater ultra-short-term HRV in obstructive sleep apnea.Scientific reports · 2020Article
- Exploring the Mediators that Promote Carotid Body Dysfunction in Type 2 Diabetes and Obesity Related Syndromes.International journal of molecular sciences · 2020Review
- Carotid Body and Metabolic Syndrome: Mechanisms and Potential Therapeutic Targets.International journal of molecular sciences · 2020Review
- Vasoactive Intestinal Polypeptide in the Carotid Body-A History of Forty Years of Research. A Mini Review.International journal of molecular sciences · 2020Review
- Advances in cellular and integrative control of oxygen and carbon dioxide homeostasis.The Journal of physiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
Abstract
The carotid bodies (CBs) are multi-modal sensory organs located bilaterally at the bifurcation of the carotid artery and innervated by the carotid sinus nerve (Hering's nerve), a branch of the IX cranial nerve. While the CBs (or embryologically analogous structures) are well known as the dominant oxygen-sensing organ in vertebrates, in mammals there is evidence that the CBs may also sense glucose and temperature, and respond to circulating hormones and other factors. Additionally, the CBs likely participate in regulating baseline levels of sympathetic tone. In this brief review, we focus on the evolution of our efforts to understand 'what else' beyond oxygen sensing the CBs do in humans.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.