Evidence map›Paper›PMID 29377063›Full record

ArticleClinical and experimental immunology2018

Measurement of Typhi Vi antibodies can be used to assess adaptive immunity in patients with immunodeficiency.

C Evans, E Bateman, R Steven, M Ponsford, A Cullinane, C Shenton, G Duthie, C Conlon, S Jolles, A P Huissoon and 7 more

Open access · bronzeAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and experimental immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Observational
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

C EvansClinical Immunology Laboratory, Oxford University Hospitals Foundation Trust, Oxford, UK.
E BatemanClinical Immunology Laboratory, Oxford University Hospitals Foundation Trust, Oxford, UK.ORCID 0000-0001-7993-2991
R StevenImmunodeficiency Centre for Wales, University Hospital of Wales, Cardiff, UK.
M PonsfordImmunodeficiency Centre for Wales, University Hospital of Wales, Cardiff, UK.
A CullinaneClinical Immunology Laboratory, Oxford University Hospitals Foundation Trust, Oxford, UK.
C ShentonClinical Immunology Laboratory, Oxford University Hospitals Foundation Trust, Oxford, UK.
G DuthieInfectious Disease Department, Oxford University Hospitals Foundation Trust, Oxford, UK.
C ConlonInfectious Disease Department, Oxford University Hospitals Foundation Trust, Oxford, UK.
S JollesImmunodeficiency Centre for Wales, University Hospital of Wales, Cardiff, UK.ORCID 0000-0002-7394-6804
A P HuissoonWest Midlands Primary Immunodeficiency Centre, Birmingham Heartlands Hospital, Birmingham, UK.
H J LonghurstDepartment of Immunology, Barts Health NHS Trust, London, UK.
T RahmanDepartment of Immunology, Barts Health NHS Trust, London, UK.
C ScottDepartment of Immunology, Barts Health NHS Trust, London, UK.
G WallisBinding Site Group Limited, Birmingham, UK.
S HardingBinding Site Group Limited, Birmingham, UK.
A R ParkerBinding Site Group Limited, Birmingham, UK.
B L FerryClinical Immunology Laboratory, Oxford University Hospitals Foundation Trust, Oxford, UK.
Oxford University Hospitals NHS Trust · GBBarts Health NHS Trust · GBUniversity Hospital of Wales · GBHeartlands Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccine-specific antibody responses are essential in the diagnosis of antibody deficiencies. Responses to Pneumovax II are used to assess the response to polysaccharide antigens, but interpretation may be complicated. Typhim Vi

Indexed as

Adaptive ImmunityAdolescentAdultAgedAged, 80 and overAntibodies, BacterialAntibody FormationEnzyme-Linked Immunosorbent AssayFemaleHumansImmunoglobulin GImmunologic Deficiency SyndromesMaleMiddle AgedPneumococcal VaccinesPolysaccharides, BacterialAntibodies, BacterialImmunoglobulin GPneumococcal VaccinesPolysaccharides, BacterialTyphoid-Paratyphoid VaccinesVi polysaccharide vaccine, typhoidadaptive immunitypneumococcalpolysaccharideTyphi Vi

Identifiers

PMID29377063
PMCPMC5980364
OpenAlexW2807391456

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.