Evidence map›Paper›PMID 29376941›Full record

ReviewJournal of fungi (Basel, Switzerland)2016

Inositol Polyphosphate Kinases, Fungal Virulence and Drug Discovery.

Cecilia Li, Sophie Lev, Adolfo Saiardi, Desmarini Desmarini, Tania C Sorrell, Julianne T Djordjevic

Open access · goldAbstract readReview
In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Arg1 frommBio · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Inositol Signaling in the Basidiomycete FungusJournal of fungi (Basel, Switzerland) · 2021
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Special Issue: Novel Antifungal Drug Discovery.Journal of fungi (Basel, Switzerland) · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Cecilia LiCentre for Infectious Diseases and Microbiology, The Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW 2145, Australia. celi4752@uni.sydney.edu.au.
Sophie LevCentre for Infectious Diseases and Microbiology, The Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW 2145, Australia. levsophie@gmail.com.
Adolfo SaiardiMedical Research Council Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, UK. dmcbado@ucl.ac.uk.ORCID 0000-0002-4351-0081
Desmarini DesmariniCentre for Infectious Diseases and Microbiology, The Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW 2145, Australia. desmarini.desmarini@sydney.edu.au.
Tania C SorrellCentre for Infectious Diseases and Microbiology, The Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW 2145, Australia. tania.sorrell@sydney.edu.au.
Julianne T DjordjevicCentre for Infectious Diseases and Microbiology, The Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW 2145, Australia. julianne.djordjevic@sydney.edu.au.
The University of Sydney · AUMRC Laboratory for Molecular Cell Biology · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Opportunistic fungi are a major cause of morbidity and mortality world-wide, particularly in immunocompromised individuals. Developing new treatments to combat invasive fungal disease is challenging given that fungal and mammalian host cells are eukaryotic, with similar organization and physiology. Even therapies targeting unique fungal cell features have limitations and drug resistance is emerging. New approaches to the development of antifungal drugs are therefore needed urgently.

Indexed as

antifungal compoundscryptococcal meningitisCryptococcus neoformansdrug discoveryfungal virulenceinositol polyphosphate kinasesinositol pyrophosphatesPP-IP5

Identifiers

PMID29376941
PMCPMC5753137
OpenAlexW2507501571

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.