Evidence map›Paper›PMID 29376828›Full record

ArticleeLife2018

Portraits of a pressure sensor.

Alexander T Chesler, Marcin Szczot

Abstract readComment
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. The Concise Guide to PHARMACOLOGY 2023/24: Ion channels.British journal of pharmacology · 2023
    Article
  3. Review
  4. The Form and Function of PIEZO2.Annual review of biochemistry · 2021
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. The plasma membrane as a mechanochemical transducer.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019
    Review
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Alexander T CheslerNational Center of Complementary and Integrative Health, National Institutes of Health, Bethesda, United States.ORCID 0000-0002-3131-0728
Marcin SzczotNational Center of Complementary and Integrative Health, National Institutes of Health, Bethesda, United States.

Funding

Studies on the molecular, cells, and circuit that underlie somatosensation and painZIAAT000028 · NCCIH · NATIONAL CENTER FOR COMPLEMENTARY & INTEGRATIVE HEALTH · PI CHESLER, ALEXANDER · 2014 to 2025
$12.0M
6 · The paper itself

Abstract

Near atomic-resolution structures have provided insights into the mechanisms by which the Piezo1 ion channel senses and responds to mechanical stimuli.

Indexed as

HumansIon ChannelsIon ChannelsbiophysicscryoEMhumanmechanosensitivitymouseneurosciencepiezo ion channelssomatosensationstructural biologyvascular system

Identifiers

PMID29376828
PMCPMC5788499

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.