Evidence map›Paper›PMID 29376199›Full record

ArticleInternational orthopaedics2018

Prophylactic negative pressure wound therapy after lower extremity fracture surgery: a pilot study.

Siem A Dingemans, Merel F N Birnie, Manouk Backes, Vincent M de Jong, Jan S Luitse, J Carel Goslings, Tim Schepers

Erratum issuedOpen access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in International orthopaedics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 8 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 8 syntheses or guidelines pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Siem A DingemansDepartment of Surgery, Academic Medical Center, Trauma Unit, Meibergdreef 9, PO Box 22660, 1100, Amsterdam, DD, Netherlands.
Merel F N BirnieDepartment of Surgery, Academic Medical Center, Trauma Unit, Meibergdreef 9, PO Box 22660, 1100, Amsterdam, DD, Netherlands.
Manouk BackesDepartment of Surgery, Academic Medical Center, Trauma Unit, Meibergdreef 9, PO Box 22660, 1100, Amsterdam, DD, Netherlands.
Vincent M de JongDepartment of Surgery, Academic Medical Center, Trauma Unit, Meibergdreef 9, PO Box 22660, 1100, Amsterdam, DD, Netherlands.
Jan S LuitseDepartment of Surgery, Academic Medical Center, Trauma Unit, Meibergdreef 9, PO Box 22660, 1100, Amsterdam, DD, Netherlands.
J Carel GoslingsDepartment of Surgery, Academic Medical Center, Trauma Unit, Meibergdreef 9, PO Box 22660, 1100, Amsterdam, DD, Netherlands.
Tim SchepersDepartment of Surgery, Academic Medical Center, Trauma Unit, Meibergdreef 9, PO Box 22660, 1100, Amsterdam, DD, Netherlands. t.schepers@amc.nl.
Academic Medical Center · NL

Funding

Smith and Nephew IIS377
6 · The paper itself

Abstract

purposeInfectious complications following lower extremity fracture surgery are a major concern and account for a substantial socio-economic burden to society. The aim of this pilot study was to investigate the feasibility of a new portable single-use negative pressure wound therapy device in patients undergoing major foot ankle surgery.

methodsPatients undergoing major foot ankle fracture surgery at a single level 1 trauma centre were eligible for this prospective case series. Patient characteristics were collected, as were fracture and surgical characteristics. Primary outcome was surgical site infection within 30 days as classified by the criteria from the Centers for Disease Control and Prevention. Patients in the prospective cohort were case-matched with a historical cohort from the same institution.

resultsSixty patients were included. In seven patients, the NPWT failed and treatment was ceased. Mean age was 44 years and 85% was ASA 1; 43% of the patients were actively smoking. Indications for surgery were midfoot, calcaneal, talar, and ankle fractures. In 53 patients, four (7.5%) surgical site infections occurred, two superficial (3.3%) and two (3.3%) deep infections. For 47 patients, a match was available. The incidence of surgical site infection did not statistically significantly differ between the prospective cohort and retrospective matched cohort (4.3 versus 14.9%, p = 0.29, respectively). This was also the case when looking at superficial and deep surgical site infections separately (0 versus 8.5%, p = 0.08, and 4.3 versus 6.4%, respectively).

conclusionWe have observed surgical site infections in 7.5% of the patients with the use of prophylactic negative pressure wound therapy. The incidence of surgical site infections was not statistically significantly lower compared to a matched historical cohort.

Indexed as

AdultAgedBones of Lower ExtremityFeasibility StudiesFemaleFractures, BoneHumansIncidenceMaleMiddle AgedNegative-Pressure Wound TherapyOrthopedic ProceduresPilot ProjectsProspective StudiesSurgical Wound InfectionClosed incisionLower extremity fracture surgeryNegative pressure wound therapyPostoperative wound infectionProphylactic

Identifiers

PMID29376199
OpenAlexW2792236330

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.