Evidence map›Paper›PMID 29376139›Full record

ArticleNPJ precision oncology2017

Fishing for cures: The alLURE of using zebrafish to develop precision oncology therapies.

Matteo Astone, Erin N Dankert, Sk Kayum Alam, Luke H Hoeppner

Open access · goldAbstract read
In one paragraph

Article in NPJ precision oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
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  12. Zebrafish Models of Paediatric Brain Tumours.International journal of molecular sciences · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Matteo AstoneThe Hormel Institute, University of Minnesota, Austin, MN, 55912.
Erin N DankertThe Hormel Institute, University of Minnesota, Austin, MN, 55912.
Sk Kayum AlamThe Hormel Institute, University of Minnesota, Austin, MN, 55912.
Luke H HoeppnerThe Hormel Institute, University of Minnesota, Austin, MN, 55912.
University of Minnesota · US

Funding

Triggering the dopamine pathway to inhibit lung cancer progressionR00CA187035 · NCI · UNIVERSITY OF MINNESOTA · PI HOEPPNER, LUKE HILBERT · 2015 to 2017
$743k
NCI NIH HHS R00 CA187035
6 · The paper itself

Abstract

Zebrafish have proven to be a valuable model to study human cancer biology with the ultimate aim of developing new therapies.

Indexed as

breast cancercancerDanio reriodrug developmentgeneticsglioblastomaleukemialiver cancerlymphomamelanomametastasisoncogenesispancreatic cancerpatient-derived xenograftsprecision oncologyprognosissolid tumorstargeted therapytransgenic modelstumortumorigenesiszebrafish

Identifiers

PMID29376139
PMCPMC5784449
OpenAlexW2769109663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.