ReviewFrontiers in public health2017
The Genetic Basis of Type 2 Diabetes in Hispanics and Latin Americans: Challenges and Opportunities.
Review in Frontiers in public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- TIGER: The gene expression regulatory variation landscape of human pancreatic islets.Cell reports · 2021Pooled it
- Trial
- Ibero-American position statement on therapeutic recommendations for the preventive management of cardiovascular complications in latin-American patients with type 2 diabetes mellitus: consensus of the prevention council of the inter-American society of cardiology (SIAC-PREVENT).Diabetology & metabolic syndrome · 2026Review
- Lessons from single cell omics: admixed American ancestry and sex confer cardiometabolic disease risk in Mexicans.Genome medicine · 2026Article
- Health Disparities Among Hispanic Patients With Type 2 Diabetes in the United States: An Educational Workshop.MedEdPORTAL : the journal of teaching and learning resources · 2026Article
- The influence ofFrontiers in nutrition · 2025Article
- Sex differences in the influence of type 2 diabetes (T2D)-related genes, parental history of T2D, and obesity on T2D development: a case-control study.Biology of sex differences · 2023Article
- Efficacy and Safety of Insulin Glargine 300 U/mL in People with Type 2 Diabetes Uncontrolled on Basal Insulin: The 26-Week Interventional, Single-Arm ARTEMIS-DM Study.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2022Article
- Type 2 Diabetes Mellitus in Latinx Populations in the United States: A Culturally Relevant Literature Review.Cureus · 2022Review
- Enlightening the molecular mechanisms of type 2 diabetes with a novel pathway clustering and pathway subnetwork approach.Turkish journal of biology = Turk biyoloji dergisi · 2022Article
- Comparison of Diabetes Mellitus Risk Factors in Mexico in 2003 and 2014.Frontiers in nutrition · 2022Article
- Genetics of type 2 diabetes mellitus in Indian and Global Population: A Review.The Egyptian journal of medical human genetics · 2022Review
- Specific amino acids but not total protein attenuate postpartum weight gain among Hispanic women from Southern California.Food science & nutrition · 2021Article
- Comparison of prevalence of diabetes complications in Brazilian and Mexican adults: a cross-sectional study.BMC endocrine disorders · 2021Article
- The Importance of Biobehavioral Research to Examine the Physiological Effects of Racial and Ethnic Discrimination in the Latinx Population.Frontiers in public health · 2021Review
- Prevention and management of CVD in LMICs: why do ethnicity, culture, and context matter?BMC medicine · 2020Article
- Ongoing challenges in access to diabetes care among the indigenous population: perspectives of individuals living in rural Guatemala.International journal for equity in health · 2019Article
- Hispanic representation in diabetes cardiovascular outcomes trials.BMJ open diabetes research & care · 2019Article
- Diabetes care in figures: current pitfalls and future scenario.The EPMA journal · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Type 2 diabetes (T2D) affects 415 million people worldwide, and has a much higher prevalence in Hispanics (16.9%), compared to non-Hispanic whites (10.2%). Genome-wide association studies and whole-genome and whole-exome sequencing studies have discovered more than 100 genetic regions associated with modified risk for T2D. However, the identified genetic factors explain a very small fraction of the estimated heritability. Until recently, little attention has been put in studying other non European populations that suffer from a higher burden of T2D, such as Hispanics/Latinos. In the past few years, genetic studies in Hispanic populations have started to provide new insights into the genetic architecture of T2D in this ancestry group. Of note, several genetic variants that are absent or very rare in non-Hispanic populations but more common in Hispanics have shown from moderate to strong association with T2D and have provided new insights into the biology of T2D, which may be ultimately useful for developing novel therapeutic strategies applicable to all populations. Studying diverse populations can also improve the ability to find the causal variants in known T2D
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.