Evidence map›Paper›PMID 29376029›Full record

ReviewFrontiers in cellular and infection microbiology2017

Hijacking of the Host Ubiquitin Network by

Jiazhang Qiu, Zhao-Qing Luo

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 80 citations in OpenAlex.

  1. Crystal structure of Legionella pneumophila glycosidase effector LegY.Acta crystallographica. Section F, Structural biology communications · 2026
    Article
  2. Molecular evolution and adaptations ofFrontiers in cellular and infection microbiology · 2026
    Review
  3. Journal of microbiology and biotechnology · 2025
    Article
  4. Article
  5. mLife · 2025
    Article
  6. Article
  7. Exploring the infection strategy ofFrontiers in plant science · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Eat or Be Eaten: Strategies Used byInfection and immunity · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Jiazhang QiuCenter of Infection and Immunity, First Hospital, Jilin University, Changchun, China.
Zhao-Qing LuoCenter of Infection and Immunity, First Hospital, Jilin University, Changchun, China.
First Hospital of Jilin University · CNJilin University · CN

Funding

Effector-mediated Ubiquitin Manipulation in Legionella Pneumophila PathogenesisR01AI127465 · NIAID · PURDUE UNIVERSITY · PI Qing Deng · 2017 to 2026
$3.4M
Probing novel innate immune detection mechanisms using an intracellular bacterialR21AI105714 · NIAID · PURDUE UNIVERSITY · PI LUO, ZHAO-QING · 2014 to 2015
$411k
NIAID NIH HHS R01 AI127465NIAID NIH HHS R21 AI105714
6 · The paper itself

Abstract

Protein ubiquitination is critical for regulation of numerous eukaryotic cellular processes such as protein homeostasis, cell cycle progression, immune response, DNA repair, and vesicular trafficking. Ubiquitination often leads to the alteration of protein stability, subcellular localization, or interaction with other proteins. Given the importance of ubiquitination in the regulation of host immunity, it is not surprising that many infectious agents have evolved strategies to interfere with the ubiquitination network with sophisticated mechanisms such as functional mimicry. The facultative intracellular pathogen

Indexed as

Host-Pathogen InteractionsImmune EvasionUbiquitinationGene Expression RegulationHumansLegionella pneumophilaLegionnaires' DiseaseType IV Secretion SystemsUbiquitinType IV Secretion SystemsUbiquitinbacterial virulencecell signalingeffectorsposttranslational modificationtype IV secretion

Identifiers

PMID29376029
PMCPMC5770618
OpenAlexW2768830479

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.