ArticleClinical and experimental reproductive medicine2017
Sperm DNA fragmentation and sex chromosome aneuploidy after swim-up versus density gradient centrifugation.
Article in Clinical and experimental reproductive medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
12 citing papers in PubMed, 26 citations in OpenAlex.
- Microfluidic Sorting Can Be Applied for Assisted Reproduction Sperm Selection in Different Cases of Semen Abnormalities.Life (Basel, Switzerland) · 2025Article
- Straining Flow Effects on Sperm Flagellar Energetics in Microfluidic Cross-Slot Traps.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Sperm Migration and Hyaluronic Acid Binding: Implications for Male Fertility Evaluation.International journal of molecular sciences · 2024Article
- Effects of sperm preparation techniques on sperm survivability and DNA fragmentation.The Journal of international medical research · 2022Article
- Cumulative live birth rates after IVF/ICSI cycles with sperm prepared by density gradient centrifugation vs. swim-up: a retrospective study using a propensity score-matching analysis.Reproductive biology and endocrinology : RB&E · 2022Article
- The Author Reply: Effect of Sperm DNA Fragmentation on Embryo Quality in Normal Responder Women in IVF and ICSI.Yonsei medical journal · 2020Article
- Mammalian spermatozoa and cumulus cells bind to a 3D model generated by recombinant zona pellucida protein-coated beads.Scientific reports · 2019Article
- Sperm selection with density gradient centrifugation and swim up: effect on DNA fragmentation in viable spermatozoa.Scientific reports · 2019Article
- Effect of Sperm DNA Fragmentation on Embryo Quality in Normal Responder Women in In Vitro Fertilization and Intracytoplasmic Sperm Injection.Yonsei medical journal · 2019Article
- Evaluation of normal morphology, DNA fragmentation, and hyaluronic acid binding ability of human spermatozoa after using four different commercial media for density gradient centrifugation.Clinical and experimental reproductive medicine · 2019Article
- MACS-annexin V cell sorting of semen samples with high TUNEL values decreases the concentration of cells with abnormal chromosomal content: a pilot study.Asian journal of andrologyArticle
- Swim-up method is superior to density gradient centrifugation for preserving sperm DNA integrity during sperm processing.Reproductive medicine and biologyArticle
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to compare the efficacy of swim-up and density gradient centrifugation (DGC) for reducing the amount of sperm with fragmented DNA, sex chromosome aneuploidy, and abnormal chromatin structure.
methodsSemen samples were obtained from 18 healthy male partners who attended infertility clinics for infertility investigations and were processed with swim-up and DGC. The percentages of sperm cells with fragmented DNA measured by the sperm chromatin dispersion test, normal sex chromosomes assessed by fluorescence
resultsThe percentage of sperm cells with fragmented DNA was significantly lower in the swim-up fraction (9.7%,
conclusionThe swim-up method is superior for enriching genetically competent sperm.
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Registered trials
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