Evidence map›Paper›PMID 29375995›Full record

ArticleInternational journal of ophthalmology2018

Intravitreal dexamethasone implants for diabetic macular edema.

Alicia Pareja-Ríos, Paloma Ruiz-de la Fuente-Rodríguez, Sergio Bonaque-González, Maribel López-Gálvez, Virginia Lozano-López, Pedro Romero-Aroca

Abstract read
In one paragraph

Article in International journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
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  4. Safety of intracameral application of moxifloxacin and dexamethasone (Vigadexa®) after phacoemulsification surgery.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
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  18. Predictive capacity of baseline hyperreflective dots on the intravitreal dexamethasone implant (Ozurdex®) outcomes in diabetic macular edema: a multicenter study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alicia Pareja-RíosUniversity Hospital of the Canary Islands, Santa Cruz de Tenerife, Islas Canarias 38320, Spain.
Paloma Ruiz-de la Fuente-RodríguezUniversity Hospital of the Canary Islands, Santa Cruz de Tenerife, Islas Canarias 38320, Spain.
Sergio Bonaque-GonzálezWooptix S.L, San Cristobal de La Laguna 38204, Spain.
Maribel López-GálvezUniversity Clinical Hospital of Valladolid, Institute of Applied Ophthalmobiology (IOBA), Valladolid 47011, Spain.
Virginia Lozano-LópezUniversity Hospital of the Canary Islands, Santa Cruz de Tenerife, Islas Canarias 38320, Spain.
Pedro Romero-ArocaUniversity Hospital Sant Joan de Reus, Tarragona 43204, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the safety and efficacy of a dexamethasone (DEX) intravitreal implant for diabetic macular edema (DME).

methodsTotally 113 eyes of 84 patients were divided in three subgroups: naive patients (

resultsSeventy-three eyes (64.5%) received a single implant, 30 (26.5%) received two implants and 10 (9%) received three implants. At baseline, average in BCVA, CMT and MV were 43.5±20.8, 462.8±145 and 12.6±2.5 respectively. These values improved significantly at 1mo (BCVA: 47.2±19.5, CMT: 339.6±120, MV: 11.11±1.4) and 3mo (BCVA: 53.2±18.1, CMT: 353.8±141, MV: 11.3±1.3) (

conclusionPatients with DEX implants show maximum efficacy at 3mo which then declined progressively, but is still better than baseline values at the end of follow-up.

Indexed as

dexamethasonediabetesdiabetic macular edemaOzurdexretina

Identifiers

PMID29375995
PMCPMC5767662

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.