Evidence map›Paper›PMID 29375972›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2018

Nanomicelle-Assisted Targeted Ocular Delivery with Enhanced Antiinflammatory Efficacy In Vivo.

Yu-Hua Weng, Xiao-Wei Ma, Jing Che, Chan Li, Juan Liu, Shi-Zhu Chen, Yu-Qin Wang, Ya-Ling Gan, Hao Chen, Zhong-Bo Hu and 2 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. OCTN2- and ATBJournal of nanobiotechnology · 2024
    Article
  11. Efficient ocular delivery of siRNAInternational journal of pharmaceutics: X · 2023
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Ocular Nanomedicine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yu-Hua WengChinese Academy of Sciences (CAS) Center for Excellence in Nanoscience National Center for Nanoscience and Technology Beijing 100190 P. R. China.
Xiao-Wei MaChinese Academy of Sciences (CAS) Center for Excellence in Nanoscience National Center for Nanoscience and Technology Beijing 100190 P. R. China.
Jing CheChinese Academy of Sciences (CAS) Center for Excellence in Nanoscience National Center for Nanoscience and Technology Beijing 100190 P. R. China.
Chan LiChinese Academy of Sciences (CAS) Center for Excellence in Nanoscience National Center for Nanoscience and Technology Beijing 100190 P. R. China.
Juan LiuChinese Academy of Sciences (CAS) Center for Excellence in Nanoscience National Center for Nanoscience and Technology Beijing 100190 P. R. China.
Shi-Zhu ChenChinese Academy of Sciences (CAS) Center for Excellence in Nanoscience National Center for Nanoscience and Technology Beijing 100190 P. R. China.
Yu-Qin WangSchool of Ophthalmology and Optometry and Eye Hospital Wenzhou Medical University Wenzhou P. R. China.
Ya-Ling GanChinese Academy of Sciences (CAS) Center for Excellence in Nanoscience National Center for Nanoscience and Technology Beijing 100190 P. R. China.
Hao ChenSchool of Ophthalmology and Optometry and Eye Hospital Wenzhou Medical University Wenzhou P. R. China.
Zhong-Bo HuCollege of Materials Science and Opto-Electronic Technology University of Chinese Academy of Sciences Beijing 100049 P. R. China.
Kai-Hui NanSchool of Ophthalmology and Optometry and Eye Hospital Wenzhou Medical University Wenzhou P. R. China.
Xing-Jie LiangChinese Academy of Sciences (CAS) Center for Excellence in Nanoscience National Center for Nanoscience and Technology Beijing 100190 P. R. China.ORCID 0000-0002-4793-1705

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ocular inflammations are common diseases that may lead to serious vision-threatening obstacles. Eye drops for antiinflammation therapy need to be administered multiple times daily at a high dosage due to the rapid precorneal removal and low bioavailability of drugs. To overcome these problems, a cRGD-functionalized DSPE-PEG

Indexed as

antiinflammationflurbiprofen nanomicellesfunctional peptideocular delivery system

Identifiers

PMID29375972
PMCPMC5770669

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.