Evidence map›Paper›PMID 29375912›Full record

Observational studyJournal of obesity2017

Predictors of Insulin Resistance in Children versus Adolescents with Obesity.

Yvette E Lentferink, Marieke A J Elst, Catherijne A J Knibbe, Marja M J van der Vorst

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Journal of obesity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

  1. Body Weight and Insulin Resistance Indicators Among Children.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Article
  2. Article
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  4. The CCR2Journal of cardiovascular development and disease · 2022
    Article
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  7. Observational
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  12. Diabetes, metabolic syndrome and obesity : targets and therapy · 2020
    Article
  13. Article
  14. Metabolic Profiles in Obese Children and Adolescents with Insulin Resistance.Open access Macedonian journal of medical sciences · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yvette E LentferinkDepartment of Pediatrics, St. Antonius Hospital, Nieuwegein/Utrecht, Postbus 2500, 3430 EM Nieuwegein, Netherlands.
Marieke A J ElstDepartment of Pediatrics, St. Antonius Hospital, Nieuwegein/Utrecht, Postbus 2500, 3430 EM Nieuwegein, Netherlands.ORCID 0000-0002-3631-0874
Catherijne A J KnibbeDepartment of Clinical Pharmacy, St. Antonius Hospital, Nieuwegein/Utrecht, Postbus 2500, 3430 EM Nieuwegein, Netherlands.
Marja M J van der VorstDepartment of Pediatrics, St. Antonius Hospital, Nieuwegein/Utrecht, Postbus 2500, 3430 EM Nieuwegein, Netherlands.ORCID 0000-0001-9581-3044
St. Antonius Ziekenhuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Obesity is a risk factor to develop metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM). Insulin resistance (IR) plays a major part in both. With increasing incidence of childhood obesity, this retrospective study aimed to identify predictors of IR in children/adolescents with obesity to optimize screening for IR. Method: Patients aged ≥ 2-≤ 18 years with obesity (BMI-SDS > 2.3) were included. IR was defined as HOMA-IR ≥ 3.4, and MetS if ≥3 of the following criteria were present: waist circumference and blood pressure ≥ 95th age percentile, triglycerides ≥ 1.7 mmol/l, HDL < 1.03 mmol/l, and fasting plasma glucose ≥ 5.6 mmol/l. Results: In total, 777 patients were included. Of the 306 children, 51, 38, and 0 were diagnosed with IR, MetS, and T2DM, respectively. Of the 471 adolescents, 223, 95, and 0 were diagnosed with IR, MetS, and T2DM, respectively. In the multivariable regression model, BMI-SDS, preterm birth, and Tanner stage were associated with IR in children (6.3 (95% CI 1.3-31.1), 5.4 (95% CI 1.4-20.5), 2.2 (95% CI 1.0-4.8)), and BMI-SDS and waist circumference in adolescents (4.0 (95% CI 1.7-9.2), 3.7 (95% CI 1.5-9.4)). Conclusion: Different IR predictors were observed in children/adolescents with obesity. These predictors can be used to optimize screening for IR in pediatric populations.

Indexed as

Insulin ResistanceAdolescentAnthropometryBlood GlucoseBlood PressureChildChild, PreschoolCross-Sectional StudiesFemaleHumansMaleNetherlandsPediatric ObesityRetrospective StudiesRisk FactorsTriglyceridesBlood GlucoseTriglycerides

Identifiers

PMID29375912
PMCPMC5742469
OpenAlexW2775667439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.