Evidence map›Paper›PMID 29375829›Full record

ArticleClinical case reports2018

DNA methylation alterations in the genome of a toddler with cri-du-chat syndrome.

Oxana Y Naumova, Sergey Y Rychkov, Tatyana V Kuznetzova, Veronika V Odintsova, Sergey A Kornilov, Elena L Grigorenko

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Oxana Y NaumovaTexas Institute for Measurement, Evaluation, and Statistics University of Houston Houston Texas.ORCID 0000-0003-0889-526X
Sergey Y RychkovLaboratory of Human Genetics Vavilov Institute of General Genetics RAS Moscow Russian Federation.
Tatyana V KuznetzovaD.O. Ott's Research Institute of Obstetrics, Gynecology and Reproductology Saint Petersburg Russian Federation.
Veronika V OdintsovaDepartment of Psychology Saint-Petersburg State University Saint Petersburg Russian Federation.
Sergey A KornilovTexas Institute for Measurement, Evaluation, and Statistics University of Houston Houston Texas.ORCID 0000-0002-8378-110X
Elena L GrigorenkoTexas Institute for Measurement, Evaluation, and Statistics University of Houston Houston Texas.ORCID 0000-0001-9646-4181
St Petersburg University · RUVavilov Institute of General Genetics · RUResearch Institute of Obstetrics and Gynecology named after D.O. Ott · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This manuscript reports on genomewide epigenetic alterations in cri-du-chat syndrome related to a partial aneusomy of chromosome 5. A systematic analysis of these alterations will open up new possibilities for the prognostic evaluation of CDCS patients and the development of new therapeutic interventions for reducing the severity of the disease.

Indexed as

case studycri‐du‐chat syndromeDNA methylationIllumina Infinium Human Methylation450

Identifiers

PMID29375829
PMCPMC5771924
OpenAlexW2770407449

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.