Evidence map›Paper›PMID 29375556›Full record

ArticleFrontiers in immunology2017

A Phase 2a Randomized Study to Evaluate the Safety and Immunogenicity of the 1790GAHB Generalized Modules for Membrane Antigen Vaccine against

Christina W Obiero, Augustin G W Ndiaye, Antonella Silvia Sciré, Bonface M Kaunyangi, Elisa Marchetti, Ann M Gone, Lena Dorothee Schütte, Daniele Riccucci, Joachim Auerbach, Allan Saul and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 107 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Antibodies Elicited by theFrontiers in immunology · 2021
    Trial
  4. Review
  5. Article
  6. Frontiers in microbiology · 2026
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Immunogenicity evaluation of altSonflex1-2-3Frontiers in immunology · 2025
    Article
  12. Article
  13. TestingPharmaceutics · 2024
    Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Shigella-Controlled Human Infection Models: Current and Future Perspectives.Current topics in microbiology and immunology · 2024
    Review
  19. Outer Membrane Vesicle Vaccine Platforms.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2024
    Review
  20. Review

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 3 countries.

Christina W ObieroKEMRI-Wellcome Trust Research Programme, Clinical Research Department, Kilifi, Kenya.
Augustin G W NdiayeGSK Vaccines Institute for Global Health, Siena, Italy.
Antonella Silvia SciréGSK Vaccines Institute for Global Health, Siena, Italy.
Bonface M KaunyangiKEMRI-Wellcome Trust Research Programme, Clinical Research Department, Kilifi, Kenya.
Elisa MarchettiGSK Vaccines Institute for Global Health, Siena, Italy.
Ann M GoneKEMRI-Wellcome Trust Research Programme, Clinical Research Department, Kilifi, Kenya.
Lena Dorothee SchütteGSK Vaccines Clinical Laboratory Sciences, Marburg, Germany.
Daniele RiccucciGSK Vaccines Institute for Global Health, Siena, Italy.
Joachim AuerbachGSK Vaccines Institute for Global Health, Siena, Italy.
Allan SaulGSK Vaccines Institute for Global Health, Siena, Italy.
Laura B MartinGSK Vaccines Institute for Global Health, Siena, Italy.
Philip BejonClinical Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Headington, United Kingdom.
Patricia NjugunaKEMRI-Wellcome Trust Research Programme, Clinical Research Department, Kilifi, Kenya.
Audino PoddaGSK Vaccines Institute for Global Health, Siena, Italy.
Toscana Life Sciences · ITKenya Medical Research Institute · KEUniversity of Oxford · GB

Funding

Medical Research Council G1002624
6 · The paper itself

Abstract

Shigellosis is a mild-to-severe diarrheal infection, caused by the genus

Indexed as

1790GAHB vaccinegeneralized modules for membrane antigenimmunogenicitysafetyShigella-endemic settingsShigella sonnei

Identifiers

PMID29375556
PMCPMC5763125
OpenAlexW2776594371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.