Evidence map›Paper›PMID 29375546›Full record

ArticleFrontiers in immunology2017

Cu,Zn Superoxide Dismutase Genes in

Kevin Ferro, Diana Ferro, Francesca Corrà, Rigers Bakiu, Gianfranco Santovito, Joachim Kurtz

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 40 citations in OpenAlex.

  1. Antioxidants (Basel, Switzerland) · 2026
    Review
  2. Non-lethal heat shock unlocksFrontiers in immunology · 2026
    Article
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  8. Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  9. Article
  10. Examining adaptive evolution of immune activity: opportunities provided by gastropods in the age of 'omics'.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021
    Review
  11. Article
  12. Article
  13. PFAS Environmental Pollution and Antioxidant Responses: An Overview of the Impact on Human Field.International journal of environmental research and public health · 2020
    Review
  14. Article
  15. Copper/Zinc Superoxide Dismutase from the Crocodile IcefishAntioxidants (Basel, Switzerland) · 2020
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Kevin FerroInstitute for Evolution and Biodiversity, University of Münster, Münster, Germany.
Diana FerroInstitute for Evolution and Biodiversity, University of Münster, Münster, Germany.
Francesca CorràDepartment of Biology, University of Padova, Padova, Italy.
Rigers BakiuDepartment of Aquaculture and Fisheries, Faculty of Agriculture and Environment, Agricultural University of Tirana, Tirana, Albania.
Gianfranco SantovitoDepartment of Biology, University of Padova, Padova, Italy.
Joachim KurtzInstitute for Evolution and Biodiversity, University of Münster, Münster, Germany.
University of Münster · DEUniversity of Padua · ITAgricultural University of Tirana · AL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The production of reactive oxygen species (ROS) is a normal consequence of the aerobic cell metabolism. Despite their high and potentially detrimental reactivity with various biomolecules, the endogenous production of ROS is a vital part of physiological, immunological, and molecular processes that contribute to fitness. The role of ROS in host-parasite interactions is frequently defined by their contribution to innate immunity as effectors, promoting parasite death during infections. In vertebrates, ROS and antioxidant system enzymes, such as superoxide dismutase (SOD) are also involved in acquired immune memory, where they are responsible for T-cell signalling, activation, proliferation, and viability. Based on recent findings, ROS are now also assumed to play a role in immune priming, i.e., a form of memory in invertebrates. In this study, the potential involvement of Cu,Zn SODs in immunity of the red flour beetle

Indexed as

Bacillus thuringiensisimmune priminginnate immunityreactive oxygen speciessuperoxide dismutaseTribolium castaneum

Identifiers

PMID29375546
PMCPMC5763126
OpenAlexW2771980577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.