ArticleFrontiers in physiology2017
Age-Related Changes in the Expression of the Circadian Clock Protein PERIOD in
Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 25 citations in OpenAlex.
- Regulation of Metabolic Rhythms by Glial Clocks.Journal of biological rhythms · 2026Article
- Multifaceted dynamics of circadian timing system influence aging and longevity.Biogerontology · 2025Review
- Stroke onset time affected outcomes in the young acute ischemic stroke patients treated with endovascular thrombectomy.Frontiers in neurology · 2025Article
- Circadian Rhythms of the Blood-Brain Barrier and Drug Delivery.Circulation research · 2024Review
- The amyloid precursor protein intracellular domain induces sleep disruptions and its nuclear localization fluctuates in circadian pacemaker neurons in Drosophila and mice.Neurobiology of disease · 2024Article
- A circadian clock regulates the blood-brain barrier across phylogeny.Vitamins and hormones · 2024Review
- Phenotypic and transcriptomic impact of expressing mammalian TET2 in theEpigenetics · 2023Article
- Systematic assessment of transcriptomic and metabolic reprogramming by blue light exposure coupled with aging.PNAS nexus · 2023Article
- What do we mean by "aging"? Questions and perspectives revealed by studies in Drosophila.Mechanisms of ageing and development · 2023Article
- Association of Circadian Clock Gene Expression with Pediatric/Adolescent Asthma and Its Comorbidities.International journal of molecular sciences · 2023Article
- Roles of peripheral clocks: lessons from the fly.FEBS letters · 2022Review
- Glia-Neurons Cross-Talk Regulated Through Autophagy.Frontiers in physiology · 2022Article
- Circadian regulation of the Drosophila astrocyte transcriptome.PLoS genetics · 2021Article
- The Glial Perspective on Sleep and Circadian Rhythms.Annual review of neuroscience · 2020Review
- Article
- Aging and the clock: Perspective from flies to humans.The European journal of neuroscience · 2020Review
- Regulation of the Blood-Brain Barrier by Circadian Rhythms and Sleep.Trends in neurosciences · 2019Review
- Loss ofFrontiers in cellular neuroscience · 2019Article
- Different Levels of Expression of the Clock Protein PER and the Glial Marker REPO in Ensheathing and Astrocyte-Like Glia of the Distal Medulla ofFrontiers in physiology · 2018Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Circadian clocks consist of molecular negative feedback loops that coordinate physiological, neurological, and behavioral variables into "circa" 24-h rhythms. Rhythms in behavioral and other circadian outputs tend to weaken during aging, as evident in progressive disruptions of sleep-wake cycles in aging organisms. However, less is known about the molecular changes in the expression of clock genes and proteins that may lead to the weakening of circadian outputs. Western blot studies have demonstrated that the expression of the core clock protein PERIOD (PER) declines in the heads of aged
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