Evidence map›Paper›PMID 29375356›Full record

ArticleFrontiers in computational neuroscience2017

Classification of Alzheimer's Disease, Mild Cognitive Impairment, and Cognitively Unimpaired Individuals Using Multi-feature Kernel Discriminant Dictionary Learning.

Qing Li, Xia Wu, Lele Xu, Kewei Chen, Li Yao, Alzheimer's Disease Neuroimaging Initiative

Abstract read
In one paragraph

Article in Frontiers in computational neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qing LiDepartment of Electronics, College of Information Science and Technology, Beijing Normal University, Beijing, China.
Xia WuDepartment of Electronics, College of Information Science and Technology, Beijing Normal University, Beijing, China.
Lele XuDepartment of Electronics, College of Information Science and Technology, Beijing Normal University, Beijing, China.
Kewei ChenBanner Alzheimer's Institute and Banner Good Samaritan PET Center, Phoenix, AZ, United States.
Li YaoDepartment of Electronics, College of Information Science and Technology, Beijing Normal University, Beijing, China.
Alzheimer's Disease Neuroimaging Initiative

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate classification of either patients with Alzheimer's disease (AD) or patients with mild cognitive impairment (MCI), the prodromal stage of AD, from cognitively unimpaired (CU) individuals is important for clinical diagnosis and adequate intervention. The current study focused on distinguishing AD or MCI from CU based on the multi-feature kernel supervised within-Class-similar discriminative dictionary learning algorithm (MKSCDDL), which we introduced in a previous study, demonstrating that MKSCDDL had superior performance in face recognition. Structural magnetic resonance imaging (sMRI), fluorodeoxyglucose (FDG) positron emission tomography (PET), and florbetapir-PET data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database were all included for classification of AD vs. CU, MCI vs. CU, as well as AD vs. MCI (113 AD patients, 110 MCI patients, and 117 CU subjects). By adopting MKSCDDL, we achieved a classification accuracy of 98.18% for AD vs. CU, 78.50% for MCI vs. CU, and 74.47% for AD vs. MCI, which in each instance was superior to results obtained using several other state-of-the-art approaches (MKL, JRC, mSRC, and mSCDDL). In addition, testing time results outperformed other high quality methods. Therefore, the results suggested that the MKSCDDL procedure is a promising tool for assisting early diagnosis of diseases using neuroimaging data.

Indexed as

Alzheimer's disease (AD)mild cognitive impairment (MCI)multimodal imagingmultiple kernel dictionary learning

Identifiers

PMID29375356
PMCPMC5767247

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.