Evidence map›Paper›PMID 29375292›Full record

ArticleFrontiers in neuroscience2017

Conductive Hydrogel Electrodes for Delivery of Long-Term High Frequency Pulses.

Naomi A Staples, Josef A Goding, Aaron D Gilmour, Kirill Y Aristovich, Phillip Byrnes-Preston, David S Holder, John W Morley, Nigel H Lovell, Daniel J Chew, Rylie A Green

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Seeing Through Muddy Water: Laser-Induced Graphene for Portable Tomography Imaging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Hydrogels in Spinal Cord Injury Repair: A Review.Frontiers in bioengineering and biotechnology · 2022
    Review
  8. Article
  9. Stretchable, Fully Polymeric Electrode Arrays for Peripheral Nerve Stimulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Article
  10. Review
  11. Graphene Oxide-Based Nanomaterials: An Insight into Retinal Prosthesis.International journal of molecular sciences · 2020
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Naomi A StaplesGraduate School of Biomedical Engineering, University of New South Wales, Sydney, NSW, Australia.
Josef A GodingGraduate School of Biomedical Engineering, University of New South Wales, Sydney, NSW, Australia.
Aaron D GilmourGraduate School of Biomedical Engineering, University of New South Wales, Sydney, NSW, Australia.
Kirill Y AristovichMedical Physics and Biomedical Engineering, University College London, London, United Kingdom.
Phillip Byrnes-PrestonGraduate School of Biomedical Engineering, University of New South Wales, Sydney, NSW, Australia.
David S HolderMedical Physics and Biomedical Engineering, University College London, London, United Kingdom.
John W MorleySchool of Medical Science, University of New South Wales, Sydney, NSW, Australia.
Nigel H LovellGraduate School of Biomedical Engineering, University of New South Wales, Sydney, NSW, Australia.
Daniel J ChewGalvani Bioelectronics, Stevenage, United Kingdom.
Rylie A GreenGraduate School of Biomedical Engineering, University of New South Wales, Sydney, NSW, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nerve block waveforms require the passage of large amounts of electrical energy at the neural interface for extended periods of time. It is desirable that such waveforms be applied chronically, consistent with the treatment of protracted immune conditions, however current metal electrode technologies are limited in their capacity to safely deliver ongoing stable blocking waveforms. Conductive hydrogel (CH) electrode coatings have been shown to improve the performance of conventional bionic devices, which use considerably lower amounts of energy than conventional metal electrodes to replace or augment sensory neuron function. In this study the application of CH materials was explored, using both a commercially available platinum iridium (PtIr) cuff electrode array and a novel low-cost stainless steel (SS) electrode array. The CH was able to significantly increase the electrochemical performance of both array types. The SS electrode coated with the CH was shown to be stable under continuous delivery of 2 mA square pulse waveforms at 40,000 Hz for 42 days. CH coatings have been shown as a beneficial electrode material compatible with long-term delivery of high current, high energy waveforms.

Indexed as

conductive hydrogelhigh frequency stimulationnerve blockneural interfacesperipheral nerve cuff array

Identifiers

PMID29375292
PMCPMC5768631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.