ArticleJournal of atherosclerosis and thrombosis2018
Additive Prognostic Value of Carotid Plaque Score to Enhance the Age, Creatinine, and Ejection Fraction Score in Patients with Acute Coronary Syndrome.
Article in Journal of atherosclerosis and thrombosis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- ACEF score and its predictive performance in coronary artery disease patients undergoing PCI: a systematic review and meta-analysis of the C-statistic.AsiaIntervention · 2026Article
- Triple Assessments of Atherosclerosis in Patients With Heterozygous Familial Hypercholesterolemia.JACC. Asia · 2025Article
- Coronary Artery and Carotid Artery Plaques in Patients With Heterozygous Familial Hypercholesterolemia.JACC. Advances · 2023Article
- Heterogeneous Carotid Plaque Predicts Cardiovascular Events after Percutaneous Coronary Intervention.Journal of atherosclerosis and thrombosis · 2023Article
- Risk Prediction Models for Ischemic Cardiovascular Outcomes in Patients with Acute Coronary Syndrome.Reviews in cardiovascular medicine · 2023Review
- Age-Bilirubin-International Normalized Ratio (INR)-Creatinine (ABIC) Score, a Potential Prognostic Model for Long-Term Mortality of CAD Patients After PCI.Journal of inflammation research · 2023Article
- Utility of atherosclerosis-associated serum antibodies against colony-stimulating factor 2 in predicting the onset of acute ischemic stroke and prognosis of colorectal cancer.Frontiers in cardiovascular medicine · 2023Article
- Nomogram and Carotid Risk Score for Predicting Moderate or High Carotid Atherosclerosis among Asymptomatic Elderly Recycling Volunteers.Diagnostics (Basel, Switzerland) · 2022Article
- The Assessment of Carotid Atherosclerotic Plaque among Young Patients with Familial Hypercholesterolemia.Internal medicine (Tokyo, Japan) · 2022Article
- Impact of concomitant peripheral artery disease on contrast-induced acute kidney injury and mortality in patients with acute coronary syndrome after percutaneous coronary intervention.Heart and vessels · 2020Observational
- Clinical Impact of Carotid Plaque Score rather than Carotid Intima-Media Thickness on Recurrence of Atherosclerotic Cardiovascular Disease Events.Journal of atherosclerosis and thrombosis · 2020Article
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Authors and funding
10 authors.
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No grant is acknowledged in the PubMed record.
Abstract
aimTo assess whether combining measurements obtained from carotid ultrasonography in addition to the age, creatinine, and ejection fraction (ACEF) score would improve the predictive ability of outcome in patients with acute coronary syndrome (ACS).
methodsWe examined 264 patients with ACS (194 men; mean age: 68±11 years) who underwent percutaneous coronary intervention. The carotid plaque score (cPS) and intima-media thickness (cIMT) were determined by carotid ultrasonography. The modified ACEF score was calculated using the following formula: (age/left ventricular ejection fraction) ＋1 point for every 10 mL/min reduction in creatinine clearance below 60 mL/min per 1.73 m
resultsDuring the median 4-year follow-up, there were 121 incidents of MACEs. Multivariate Cox proportional hazard regression analysis revealed that cPS ≥9.8 (hazard ratio [HR], 1.52; 95% confidence interval [CI], 1.01-2.31) and ACEF score ≥1.20 (HR, 1.62; 95% CI, 1.11-2.39) were significantly associated with MACEs, whereas cIMT was not. When the new combined risk score was calculated by multiplying the cPS by the modified ACEF score, the freedom from MACEs at 5 years was 71% and 31% for the lower and higher scores, respectively (p＜0.001). The area under the receiver-operating characteristic curve for MACEs for the ACEF score, cPS, and combined risk score were 0.65, 0.66, and 0.71, respectively (p＜0.05).
conclusionThe cPS offers an incremental predictive value when combined to the simple ACEF score in ACS.
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