Evidence map›Paper›PMID 29375034›Full record

ArticleLipids in health and disease2018

Diet/lifestyle and risk of diabetes and glycemic traits: a Mendelian randomization study.

Renyu Ding, Tao Huang, Jiali Han

Open access · goldAbstract read
In one paragraph

Article in Lipids in health and disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Renyu DingDepartment of Intensive Care Medicine, The First Hospital of China Medical University, Liaoning, 110001, China.
Tao HuangDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, 100191, China. huangtao@bjmu.edu.cn.
Jiali HanDepartment of Otolaryngology, The First Hospital of China Medical University, Liaoning, 110001, China. jiali_han@163.com.
China Medical University · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObservational studies have demonstrated diet/lifestyle play roles in development of type 2 diabetes (T2DM); however, it remains unclear whether these relationships are causal.

methodsA two-sample MR approach was used to examine the causal effect of diet/lifestyle upon risk of T2DM and glycemic traits.

resultsThe protein intake-increasing allele C of FTO was significant associated with higher risk of T2DM (Beta ± SE = 0.104 ± 0.014, P = 4.40 × 10

conclusionsThese results provide evidence supporting a causal role for higher protein intake and smoking cession in T2DM. Our study provides further rationale for individuals at risk for diabetes to keep healthy lifestyle.

Indexed as

Smoking CessationAlpha-Ketoglutarate-Dependent Dioxygenase FTODiabetes Mellitus, Type 2Diet, High-ProteinHumansLife StyleMendelian Randomization AnalysisPolymorphism, Single NucleotideAlpha-Ketoglutarate-Dependent Dioxygenase FTOFTO protein, human

Identifiers

PMID29375034
PMCPMC5787924
OpenAlexW2785644002

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.