Evidence map›Paper›PMID 29374791›Full record

ReviewLung2018

Recent Advances in Bronchopulmonary Dysplasia: Pathophysiology, Prevention, and Treatment.

Jung S Hwang, Virender K Rehan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Lung, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 123 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
123citing papers in PubMed, 7 pooled it
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

123 citing papers in PubMed, 7 syntheses or guidelines pooled it, 219 citations in OpenAlex.

  1. Systemic steroids and bronchopulmonary dysplasia: a systematic review and meta-analysis.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Pooled it
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  4. Association betweenFrontiers in pediatrics · 2024
    Pooled it
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  8. Article
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  10. Trajectory of lung ultrasound scores in preterm infants at risk for bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
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  15. Sex, hormones, and lung health.Physiological reviews · 2026
    Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article

63 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jung S HwangDepartment of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, David Geffen School of Medicine at UCLA, 1124 West Carson Street, Torrance, CA, 90502, USA.
Virender K RehanDepartment of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, David Geffen School of Medicine at UCLA, 1124 West Carson Street, Torrance, CA, 90502, USA. vrehan@labiomed.org.ORCID 0000-0002-8948-8967
The Lundquist Institute · US

Funding

Developmental Nicotine Exposure & Transgenerationally Altered Lung PhenotypeR01HL127237 · NHLBI · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI REHAN, VIRENDER K · 2016 to 2019
$1.8M
Fibroblast Cell Signaling in Utero Nicotine-Induced Lung InjuryR01HD051857 · NICHD · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI REHAN, VIRENDER K · 2008 to 2012
$1.7M
Molecular Basis of Childhood Asthma Following Perinatal Vitamin D DeficiencyR21HL107118 · NHLBI · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI REHAN, VIRENDER K · 2011 to 2012
$377k
In Utero Nicotine Exposure & Transgenerational Transmission of AsthmaR21HD071731 · NICHD · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI REHAN, VIRENDER K · 2012 to 2013
$369k
NHLBI NIH HHS R01 HL127237NHLBI NIH HHS R21 HL107118NICHD NIH HHS R01 HD051857NICHD NIH HHS R21 HD071731
6 · The paper itself

Abstract

Bronchopulmonary dysplasia (BPD) is potentially one of the most devastating conditions in premature infants with longstanding consequences involving multiple organ systems including adverse effects on pulmonary function and neurodevelopmental outcome. Here we review recent studies in the field to summarize the progress made in understanding in the pathophysiology, prognosis, prevention, and treatment of BPD in the last decade. The work reviewed includes the progress in understanding its pathobiology, genomic studies, ventilatory strategies, outcomes, and therapeutic interventions. We expect that this review will help guide clinicians to treat premature infants at risk for BPD better and lead researchers to initiate further studies in the field.

Indexed as

Bronchopulmonary DysplasiaLungAnimalsGenetic Predisposition to DiseaseGestational AgeHumansInfant, NewbornInfant, PrematurePhenotypePremature BirthPrognosisRespiration, ArtificialRisk FactorsTreatment OutcomeBronchopulmonary dysplasiaChronic lung disease of prematurityLung injuryPPARγ

Identifiers

PMID29374791
PMCPMC5856637
OpenAlexW2792811894

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.