Evidence map›Paper›PMID 29374674›Full record

Trial reportBMJ open2018

TEXT messages to improve MEDication adherence and Secondary prevention (TEXTMEDS) after acute coronary syndrome: a randomised clinical trial protocol.

Clara K Chow, Aravinda Thiagalingam, Karla Santo, Cindy Kok, Jay Thakkar, Sandrine Stepien, Laurent Billot, Stephen Jan, Rohina Joshi, Graham S Hillis and 15 more

Abstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  12. BMJ open · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Clara K ChowSydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0003-4693-0038
Aravinda ThiagalingamSydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Karla SantoSydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0001-9047-8865
Cindy KokSydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0001-8937-8066
Jay ThakkarSydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Sandrine StepienSydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Laurent BillotSydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Stephen JanSydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Rohina JoshiSydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Graham S HillisDepartment of Cardiology, School of Medicine and Pharmacology, University of Western Australia, Royal Perth Hospital, Perth, WA, Australia.
David BriegerSydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Derek P ChewDepartment of Cardiology, Flinders University, Adelaide, Australia.
Karin RådholmDivision of Community Medicine, Primary Care, Department of Medicine and Health Sciences, Faculty of Health Sciences, Department of Local Care West, County Council of Östergötland, Linköping University, Linköping, Sweden.
John J AthertonDepartment of Cardiology, Royal Brisbane and Women's Hospital and University of Queensland School of Medicine, Brisbane, QLD, Australia.
Ravinay BhindiDepartment of Cardiology, Royal North Shore Hospital, St Leonards, NSW, Australia.
Nicholas CollinsDeaprtment of Cardiology, John Hunter Hospital, Newcastle, NSW, Australia.
Steven CoverdaleDepartment of Cardiology, Sunshine Coast University Hospital, Birtinya, QLD, Australia.
Christian Hamilton-CraigDepartment of Cardiology, The Prince Charles Hospital and University of Queensland, Brisbane, QLD, Australia.
Nadarajah KangaharanDepartment of Cardiology, Royal Darwin Hospital, Darwin, NT, Australia.
Andrew MaioranaSchool of Physiotherapy and Exercise Science, Curtin University and Fiona Stanley Hospital, Perth, WA, Australia.
Michelle McGradyDepartment of Cardiology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.
Pratap ShettyDepartment of Cardiology, Wollongong Hospital, Wollongong, NSW, Australia.
Peter ThompsonDepartment of Cardiology, Sir Charles Gairdner Hospital, Pert, WA, Australia.
Anthony RogersSydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Julie RedfernSydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIdentifying simple, low-cost and scalable means of supporting lifestyle change and medication adherence for patients following a cardiovascular (CV) event is important.

objectiveThe TEXTMEDS (TEXT messages to improve MEDication adherence and Secondary prevention) study aims to investigate whether a cardiac education and support programme sent via mobile phone text message improves medication adherence and risk factor levels in patients following an acute coronary syndrome (ACS). STUDY

designA single-blind, multicentre, randomised clinical trial of 1400 patients after an ACS with 12 months follow-up. The intervention group will receive multiple weekly text messages that provide information, motivation, support to adhere to medications, quit smoking (if relevant) and recommendations for healthy diet and exercise. The primary endpoint is the percentage of patients who are adherent to cardioprotective medications and the key secondary outcomes are mean systolic blood pressure (BP) and low-density lipoprotein cholesterol. Secondary outcomes will also include total cholesterol, mean diastolic BP, the percentage of participants who are adherent to each cardioprotective medication class, the percentage of participants who achieve target levels of CV risk factors, major vascular events, hospital readmissions and all-cause mortality. The study will be augmented by formal economic and process evaluations to assess acceptability, utility and cost-effectiveness. SUMMARY: The study will provide multicentre randomised trial evidence of the effects of a text message-based programme on cardioprotective medication adherence and levels of CV risk factors. ETHICS AND DISSEMINATION: Primary ethics approval was received from Western Sydney Local Health District Human Research Ethics Committee (HREC2012/12/4.1 (3648) AU RED HREC/13/WMEAD/15). Results will be disseminated via peer-reviewed publications and presentations at international conferences. TRIAL REGISTRATION NUMBER: ACTRN12613000793718; Pre-results.

Indexed as

Medication AdherenceText MessagingAcute Coronary SyndromeBlood PressureCell PhoneCholesterol, LDLDietExerciseFemaleHealth PromotionHumansLife StyleMaleMotivationPatient Education as TopicPatient ReadmissionCholesterol, LDLcardiovascular risk factorscoronary heart diseasemedication adherencemhealthsecondary preventiontext message

Identifiers

PMID29374674
PMCPMC5829769

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.