ReviewPediatric nephrology (Berlin, Germany)2018
Pediatric acute kidney injury and the subsequent risk for chronic kidney disease: is there cause for alarm?
Review in Pediatric nephrology (Berlin, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Pediatric Postoperative Acute Kidney Injury After Noncardiac Surgery: A Systematic Review and Meta-Analysis.Paediatric anaesthesia · 2026Pooled it
- Acute kidney injury due to diarrhoeal diseases in children: a systematic review.BMJ paediatrics open · 2026Pooled it
- Risk factors for chronic kidney disease progression in VACTERL-association Korean patients: a retrospective study.Childhood kidney diseases · 2026Article
- Racial, Ethnic, and Neighborhood Disparities in Acute Kidney Injury in Pediatric Acute Leukemia.Cancer medicine · 2026Article
- Effects of induction-phase acute kidney injury and age at diagnosis on chronic kidney disease in pediatric acute lymphoblastic leukemia: a time-to-event cohort study.Clinical and experimental pediatrics · 2026Article
- Kidney care at NICU discharge and follow-up recommendations for preterm infants<34 weeks.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- A Child With Anuric Acute Kidney Injury With Subsequent Hypertensive Encephalopathy: A Case Report.Cureus · 2025Article
- Rhabdomyolysis in Children: A State-of-the-Art Review.Children (Basel, Switzerland) · 2025Review
- Kidney and blood pressure outcomes 11 years after pediatric critical illness and longitudinal impact of AKI: a prospective cohort study.Pediatric nephrology (Berlin, Germany) · 2025Article
- Global, regional, and national burden of acute glomerulonephritis in children and adolescents: 1990-2021 analysis and future projections.Frontiers in public health · 2025Article
- Risk factors and renal outcomes of AKI in children with secondary steroid-resistant nephrotic syndrome.Renal failure · 2024Article
- Pediatric acute kidney injury and adverse health outcomes: using a foundational framework to evaluate a causal link.Pediatric nephrology (Berlin, Germany) · 2024Review
- Acute kidney injury in hospitalized children in 20 hospitals of China's Hunan Province: a cross-sectional survey.Renal failure · 2024Article
- Acute Kidney Injury in Children: Classification, Recognition and Treatment Principles.Children (Basel, Switzerland) · 2024Review
- Kidney Health Monitoring in Neonatal Intensive Care Unit Graduates: A Modified Delphi Consensus Statement.JAMA network open · 2024Article
- Acute kidney injury in neonates with hypoxic ischemic encephalopathy based on serum creatinine decline compared to KDIGO criteria.Pediatric nephrology (Berlin, Germany) · 2024Article
- Epidemiology of acute kidney injury in children: a report from the 26th Acute Disease Quality Initiative (ADQI) consensus conference.Pediatric nephrology (Berlin, Germany) · 2024Article
- Acute and chronic kidney injury during therapy for pediatric acute leukemia: A report from the Leukemia Electronic Abstraction of Records Network (LEARN).Pediatric blood & cancer · 2023Article
- Urine Quantification Following Furosemide for Severe Acute Kidney Injury Prediction in Critically Ill Children.Journal of pediatric intensive care · 2023Article
- Patient level factors increase risk of acute kidney disease in hospitalized children with acute kidney injury.Pediatric nephrology (Berlin, Germany) · 2023Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute kidney injury (AKI) is characterized clinically as an abrupt decline in renal function marked by reduced excretion of waste products, disordered electrolytes, and disrupted fluid homeostasis. The recent development of a standardized AKI definition has transformed our understanding of AKI epidemiology and outcomes. We now know that in the short term, children with AKI experience greater morbidity and mortality; additionally, observational studies have established that chronic renal sequelae are far more common after AKI events than previously realized. Many of these studies suggest that patients who develop AKI are at greater risk for the subsequent development of chronic kidney disease (CKD). The goal of this review is to critically evaluate the data regarding the association between AKI and CKD in children. Additionally, we describe best practice approaches for future studies, including the use of consensus AKI criteria, the application of rigorous definitions for CKD and renal sequelae, and the inclusion of non-AKI comparator groups. Finally, based upon existing data, we suggest an archetypal approach to follow-up care for the AKI survivors who may be at greater CKD risk, including children with more severe AKI, those who endure repeated AKI episodes, patients who do not experience full recovery, and those with pre-existing CKD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.