Evidence map›Paper›PMID 29374106›Full record

ArticleStroke2018

Comorbid Psychiatric Disease Is Associated With Lower Rates of Thrombolysis in Ischemic Stroke.

Diana M Bongiorno, Gail L Daumit, Rebecca F Gottesman, Roland Faigle

Open access · bronzeAbstract read
In one paragraph

Article in Stroke, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Differences in TAVR Utilization in Aortic Stenosis Among Patients With and Without Psychiatric Comorbidities.Journal of the Society for Cardiovascular Angiography & Interventions · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Why are somatic diseases in bipolar disorder insufficiently treated?International journal of bipolar disorders · 2019
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Diana M BongiornoFrom the Johns Hopkins University School of Medicine, Baltimore, MD (D.M.B.); and Division of General Internal Medicine (G.L.D.) and Department of Neurology (R.F.G., R.F.), Johns Hopkins University School of Medicine, Baltimore, MD.
Gail L DaumitFrom the Johns Hopkins University School of Medicine, Baltimore, MD (D.M.B.); and Division of General Internal Medicine (G.L.D.) and Department of Neurology (R.F.G., R.F.), Johns Hopkins University School of Medicine, Baltimore, MD.
Rebecca F GottesmanFrom the Johns Hopkins University School of Medicine, Baltimore, MD (D.M.B.); and Division of General Internal Medicine (G.L.D.) and Department of Neurology (R.F.G., R.F.), Johns Hopkins University School of Medicine, Baltimore, MD.
Roland FaigleFrom the Johns Hopkins University School of Medicine, Baltimore, MD (D.M.B.); and Division of General Internal Medicine (G.L.D.) and Department of Neurology (R.F.G., R.F.), Johns Hopkins University School of Medicine, Baltimore, MD. rfaigle1@jhmi.edu.
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

Developing and Translating Interventions to Decrease Mortality Disparities in SMIK24MH093763 · NIMH · JOHNS HOPKINS UNIVERSITY · PI DAUMIT, GAIL L. · 2012 to 2016
$830k
Neuroepidemiology of the vascular contribution to cognitive impairment and Alzheimer's diseaseK24AG052573 · NIA · JOHNS HOPKINS UNIVERSITY · PI GOTTESMAN, REBECCA F · 2016 to 2020
$803k
Mechanisms underlying race disparities in gastrostomy placement after strokeK23NS101124 · NINDS · JOHNS HOPKINS UNIVERSITY · PI FAIGLE, ROMANUS ROLAND · 2017 to 2020
$799k
NIA NIH HHS K24 AG052573NIMH NIH HHS K24 MH093763NINDS NIH HHS K23 NS101124
6 · The paper itself

Abstract

background and purposeIntravenous thrombolysis (IVT) improves outcomes after acute ischemic stroke but is underused in certain patient populations. Mental illness is pervasive in the United States, and patients with comorbid psychiatric disease experience inequities in treatment for a range of conditions. We aimed to determine whether comorbid psychiatric disease is associated with differences in IVT use in acute ischemic stroke.

methodsAcute ischemic stroke admissions between 2007 and 2011 were identified in the Nationwide Inpatient Sample. Psychiatric disease was defined by

resultsOf the 325 009 ischemic stroke cases meeting inclusion criteria, 12.8% had any of the specified psychiatric comorbidities. IVT was used in 3.6% of those with, and 4.4% of those without, psychiatric disease (

conclusionsAcute ischemic stroke patients with comorbid psychiatric disease have significantly lower odds of IVT. Understanding barriers to IVT use in such patients may help in developing interventions to increase access to evidence-based stroke care.

Indexed as

Brain IschemiaDatabases, FactualMental DisordersStrokeThrombolytic TherapyAgedAged, 80 and overFemaleHumansMaleMiddle Agedanxietydepressionhealthcare disparitiesmental disordersschizophreniastrokethrombolytic therapy

Identifiers

PMID29374106
PMCPMC5829001
OpenAlexW2790546467

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.