Evidence map›Paper›PMID 29374061›Full record

ArticleThe Journal of biological chemistry2018

Leptin enhances hypothalamic lactate dehydrogenase A (LDHA)-dependent glucose sensing to lower glucose production in high-fat-fed rats.

Mona A Abraham, Mozhgan Rasti, Paige V Bauer, Tony K T Lam

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 24 citations in OpenAlex.

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  20. Endocannabinoids in Body Weight Control.Pharmaceuticals (Basel, Switzerland) · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Mona A AbrahamFrom the Toronto General Hospital Research Institute, University Health Network, Toronto M5G 1L7, Canada.
Mozhgan RastiFrom the Toronto General Hospital Research Institute, University Health Network, Toronto M5G 1L7, Canada.
Paige V BauerFrom the Toronto General Hospital Research Institute, University Health Network, Toronto M5G 1L7, Canada.
Tony K T LamFrom the Toronto General Hospital Research Institute, University Health Network, Toronto M5G 1L7, Canada, tony.lam@uhnres.utoronto.ca.
Toronto General Hospital · CAUniversity Health Network · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The responsiveness of glucose sensing

Indexed as

AnimalsDiet, High-FatGene Expression Regulation, EnzymologicGlucoseGlucose IntoleranceGlucose Tolerance TestHomeostasisHypothalamusInsulin ResistanceLeptinL-Lactate DehydrogenaseMaleRatsRats, Sprague-DawleyGlucoseLeptinL-Lactate Dehydrogenasebrainglucoseglucose metabolismglucose productionglucose sensinghypothalamusLDHAleptin

Identifiers

PMID29374061
PMCPMC5857974
OpenAlexW2785164586

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.