Evidence map›Paper›PMID 29373543›Full record

ReviewAntioxidants (Basel, Switzerland)2018

Vitamin E as an Antioxidant in Female Reproductive Health.

Siti Syairah Mohd Mutalip, Sharaniza Ab-Rahim, Mohd Hamim Rajikin

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05471453 (To Investigate the Effectiveness of Adjuvant Supplements Prior to in Vitro Fertilization Cycles), which is not on this map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05471453 nacompletednot on this mapstarted 2022, after this paper: background citation

To Investigate the Effectiveness of Adjuvant Supplements Prior to in Vitro Fertilization Cycles

TypeinterventionalSponsorKaohsiung Veterans General Hospital.Ran2022 to 2023Enrolled70ConditionsDietary SupplementsArmsDHEA, DHEA+CoQ10+Tocotrienol
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 87 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Siti Syairah Mohd MutalipFaculty of Pharmacy, Universiti Teknologi MARA (UiTM) Puncak Alam Campus, Selangor 42300, Malaysia. syairah@puncakalam.uitm.edu.my.ORCID 0000-0002-4104-518X
Sharaniza Ab-RahimFaculty of Medicine, Universiti Teknologi MARA (UiTM) Sg. Buloh Campus, Selangor 42300, Malaysia. sharaniza_abrahim@salam.uitm.edu.my.
Mohd Hamim RajikinFaculty of Medicine, Universiti Teknologi MARA (UiTM) Sg. Buloh Campus, Selangor 42300, Malaysia. hamim400@salam.uitm.edu.my.
Universiti Teknologi MARA · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin E was first discovered in 1922 as a substance necessary for reproduction. Following this discovery, vitamin E was extensively studied, and it has become widely known as a powerful lipid-soluble antioxidant. There has been increasing interest in the role of vitamin E as an antioxidant, as it has been discovered to lower body cholesterol levels and act as an anticancer agent. Numerous studies have reported that vitamin E exhibits anti-proliferative, anti-survival, pro-apoptotic, and anti-angiogenic effects in cancer, as well as anti-inflammatory activities. There are various reports on the benefits of vitamin E on health in general. However, despite it being initially discovered as a vitamin necessary for reproduction, to date, studies relating to its effects in this area are lacking. Hence, this paper was written with the intention of providing a review of the known roles of vitamin E as an antioxidant in female reproductive health.

Indexed as

antioxidantreproductiontocopheroltocotrienolvitamin E

Identifiers

PMID29373543
PMCPMC5836012
OpenAlexW2794002751

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.