Evidence map›Paper›PMID 29373537›Full record

ArticlePharmaceutics2018

Pharmacokinetics and Pharmacodynamics of (S)-Ketoprofen Co-Administered with Caffeine: A Preclinical Study in Arthritic Rats.

Raúl Medina-López, Nancy Vara-Gama, Olivia Soria-Arteche, Luis A Moreno-Rocha, Francisco J López-Muñoz

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Synergistic Interaction BetweenPharmaceuticals (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Clinical Management of Pain in Rodents.Comparative medicine · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Raúl Medina-LópezDepartamento Sistemas Biologicos Universidad Autonoma Metropolitana-Xochimilco, Calz. del Hueso 1100, Col. Villa Quietud, Mexico City 04960, Mexico. rmlopez@correo.xoc.uam.mx.ORCID 0000-0002-4159-8403
Nancy Vara-GamaDepartamento Sistemas Biologicos Universidad Autonoma Metropolitana-Xochimilco, Calz. del Hueso 1100, Col. Villa Quietud, Mexico City 04960, Mexico. inukiniro@yahoo.com.mx.
Olivia Soria-ArtecheDepartamento Sistemas Biologicos Universidad Autonoma Metropolitana-Xochimilco, Calz. del Hueso 1100, Col. Villa Quietud, Mexico City 04960, Mexico. soriao@correo.xoc.uam.mx.
Luis A Moreno-RochaDepartamento Sistemas Biologicos Universidad Autonoma Metropolitana-Xochimilco, Calz. del Hueso 1100, Col. Villa Quietud, Mexico City 04960, Mexico. alfonso.moreno72@gmail.com.
Francisco J López-MuñozLaboratorio No. 7 "Dolor y Analgesia" del Departamento de Farmacobiologia, Cinvestav-Sede Sur, Calz. de los Tenorios No. 235, Col. Granjas Coapa, Mexico City 14330, Mexico. flopezm2@gmail.com.
Universidad Autónoma Metropolitana · MXCentro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of the present study was to determine whether caffeine modifies the pharmacokinetics and pharmacodynamics of (

Indexed as

caffeinepharmacodynamicspharmacokineticsPIFIR model(S)-ketoprofen

Identifiers

PMID29373537
PMCPMC5874833
OpenAlexW2788027224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.