Evidence map›Paper›PMID 29373533›Full record

ArticleNutrients2018

Suppression of Fatty Acid and Triglyceride Synthesis by the Flavonoid Orientin through Decrease of C/EBPδ Expression and Inhibition of PI3K/Akt-FOXO1 Signaling in Adipocytes.

Shiori Nagai, Chihiro Matsumoto, Makio Shibano, Ko Fujimori

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Adrenal lipoma formation via PI(3,4,5)PProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Orientin Prolongs the Longevity ofOxidative medicine and cellular longevity · 2022
    Article
  15. Article
  16. Review
  17. Article
  18. Natural Products as Modulators of Sirtuins.Molecules (Basel, Switzerland) · 2020
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shiori NagaiDepartment of Pathobiochemistry, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan. oups0645@gmail.com.
Chihiro MatsumotoDepartment of Pathobiochemistry, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan. e17904@gap.oups.ac.jp.
Makio ShibanoDepartment of Pharmacognosy, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan. shibano@gly.oups.ac.jp.
Ko FujimoriDepartment of Pathobiochemistry, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan. fujimori@gly.oups.ac.jp.ORCID 0000-0002-2506-0769
Osaka University of Pharmaceutical Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant flavonoids have a variety of biological properties. In a previous study, we found that the tea of the Asian dayflower,

Indexed as

3-Phosphoinositide-Dependent Protein Kinases3T3-L1 CellsAdipocytesAdipogenesisAnimalsAnti-Obesity AgentsCCAAT-Enhancer-Binding Protein-deltaCCAAT-Enhancer-Binding ProteinsFlavonoidsForkhead Box Protein O1Gene Expression Regulation, DevelopmentalGlucosidesGlycerolLipolysisMicePhosphorylation3-Phosphoinositide-Dependent Protein KinasesAnti-Obesity AgentsCCAAT-Enhancer-Binding Protein-deltaCCAAT-Enhancer-Binding ProteinsCEBPA protein, mouseCebpd protein, mouseFlavonoidsForkhead Box Protein O1Foxo1 protein, mouseGlucosidesGlycerolorientinPPAR gammaProto-Oncogene Proteins c-aktTriglyceridesadipogenesisC/EBPδFOXO1orientinPI3K/Akt

Identifiers

PMID29373533
PMCPMC5852706
OpenAlexW2791165180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.