Evidence map›Paper›PMID 29373510›Full record

ReviewJournal of functional biomaterials2018

Advances in Degradable Embolic Microspheres: A State of the Art Review.

Jensen Doucet, Lauren Kiri, Kathleen O'Connell, Sharon Kehoe, Robert J Lewandowski, David M Liu, Robert J Abraham, Daniel Boyd

Abstract readReview
In one paragraph

Review in Journal of functional biomaterials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Embolic Agents: Particles.Seminars in interventional radiology · 2023
    Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Emerging Embolic Agents in Endovascular Embolization: An Overview.Progress in biomedical engineering (Bristol, England) · 2020
    Article
  19. Advances in Biomaterials and Technologies for Vascular Embolization.Advanced materials (Deerfield Beach, Fla.) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jensen DoucetSchool of Biomedical Engineering, Dalhousie University, Halifax, NS B3H 4R2, Canada. doucet.jensen@dal.ca.
Lauren KiriDepartment of Applied Oral Sciences, Faculty of Dentistry, 5981 University Avenue, P.O. BOX 15000, Halifax, NS B3H 4R2, Canada. lekiri@gmail.com.
Kathleen O'ConnellDepartment of Applied Oral Sciences, Faculty of Dentistry, 5981 University Avenue, P.O. BOX 15000, Halifax, NS B3H 4R2, Canada. K.OConnell@dal.ca.
Sharon KehoeABK Biomedical Inc., Unit 32, 155 Chain Lake Drive, Halifax, NS B3S 1B3, Canada. s.kehoe@abkbiomedical.com.
Robert J LewandowskiDepartment of Radiology, Division of Vascular and Interventional Radiology, Fienberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. r-lewandowski@northwestern.edu.
David M LiuDepartment of Radiology, University of British Columbia, Vancouver, BC V6T 1Z4, Canada. Davidmliu@gmail.com.
Robert J AbrahamInterventional Radiology and Diagnostic Imaging Department, Room 3316, Halifax Infirmary Site, QEII Health Sciences Center, 1796 Summer St, Halifax, NS B3H 3A7, Canada. robert.abraham@dal.ca.
Daniel BoydABK Biomedical Inc., Unit 32, 155 Chain Lake Drive, Halifax, NS B3S 1B3, Canada. D.Boyd@dal.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Considerable efforts have been placed on the development of degradable microspheres for use in transarterial embolization indications. Using the guidance of the U.S. Food and Drug Administration (FDA) special controls document for the preclinical evaluation of vascular embolization devices, this review consolidates all relevant data pertaining to novel degradable microsphere technologies for bland embolization into a single reference. This review emphasizes intended use, chemical composition, degradative mechanisms, and pre-clinical safety, efficacy, and performance, while summarizing the key advantages and disadvantages for each degradable technology that is currently under development for transarterial embolization. This review is intended to provide an inclusive reference for clinicians that may facilitate an understanding of clinical and technical concepts related to this field of interventional radiology. For materials scientists, this review highlights innovative devices and current evaluation methodologies (i.e., preclinical models), and is designed to be instructive in the development of innovative/new technologies and evaluation methodologies.

Indexed as

bioresorbabledegradableembolizationmicrosphereresorbable

Identifiers

PMID29373510
PMCPMC5872100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.