ReviewBiological psychiatry2018
Impact of Sleep and Circadian Rhythms on Addiction Vulnerability in Adolescents.
Review in Biological psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
101 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Objective and subjective measurement of sleep in people who use substances: Emerging evidence and recommendations from a systematic review.Journal of sleep research · 2025Pooled it
- Neuroscience-informed classification of prevention interventions in substance use disorders: An RDoC-based approach.Neuroscience and biobehavioral reviews · 2024Pooled it
- The efficacy of cognitive behavioral therapy for insomnia in adolescents: a systematic review and meta-analysis of randomized controlled trials.Frontiers in public health · 2024Pooled it
- Leveraging Ecological Momentary Assessment to Examine Bi-directional Associations Between Sleep Quality, Adolescent/Young Adult Alcohol Craving and Use.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2023Trial
- Multivariate associations between sleep patterns and self-regulation in adolescence: Canonical correlation analysis across ABCD and NCANDA cohorts.Chronobiology international · 2026Article
- Subjective Sleep Timing and Social Jet Lag Relate to Neural Activation During Reward Feedback in Adolescence.Journal of sleep research · 2026Article
- Central and Bridge Symptoms of Internet Gaming Disorder, Social Jet Lag, and Insomnia Among College Students: Cross-Sectional Network Analysis.JMIR serious games · 2026Article
- Blunted light exposure amplitudes in patients with opioid use disorder.Npj biological timing and sleep · 2026Article
- Acute and persistent sex-dependent disruptions of sleep-wake architecture induced by fentanyl self-administration in mice.Neuropharmacology · 2026Article
- Acute Sleep Deprivation in Adolescence Produces Transcriptional Changes in the Orexin System and Regulates Motivation for Reward.Biological psychiatry global open science · 2026Article
- Sleep deprivation and memory: A neurobiological perspective.IBRO neuroscience reports · 2026Article
- Sleep regulates drug seeking and relapse - a perspective.Molecular psychiatry · 2026Review
- Identification of biological rhythm disorder profiles and associated problematic digital behaviors among university students: a latent profile analysis.BMC psychology · 2026Article
- Circadian rhythm-related miR-6883-5p suppresses enzalutamide-resistant prostate cancer.Non-coding RNA research · 2026Article
- Adolescent circadian sleep health: a review of multimodal assessment strategies and clinical implications.Frontiers in sleep · 2026Review
- Non-linear relationship between social jetlag and depressive symptoms among Chinese college students.Scientific reports · 2025Article
- Sleep as a Protective Factor: Multiple Forms of Discrimination and Substance Use Intention Among Racially and Ethnically Minoritized United States Youth.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025Article
- Findings and Methodological Shortcomings of Investigations Concerning the Relationship Between Sleep Duration and Blood Pressure: A Comprehensive Narrative Review.Journal of cardiovascular development and disease · 2025Review
- Associations between multiple sleep dimensions and suicide and non-suicidal self-injury: a cross-sectional study of 3828 Chinese young people.Social psychiatry and psychiatric epidemiology · 2025Article
- Longitudinal Associations Between Sleep Disturbance Trajectories and Internet Gaming Disorder Mediated by Self-Control: A Six-Wave Longitudinal Investigation.Psychology research and behavior management · 2025Article
41 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
9 authors.
Funding
Abstract
Sleep homeostasis and circadian function are important maintaining factors for optimal health and well-being. Conversely, sleep and circadian disruptions are implicated in a variety of adverse health outcomes, including substance use disorders. These risks are particularly salient during adolescence. Adolescents require 8 to 10 hours of sleep per night, although few consistently achieve these durations. A mismatch between developmental changes and social/environmental demands contributes to inadequate sleep. Homeostatic sleep drive takes longer to build, circadian rhythms naturally become delayed, and sensitivity to the phase-shifting effects of light increases, all of which lead to an evening preference (i.e., chronotype) during adolescence. In addition, school start times are often earlier in adolescence and the use of electronic devices at night increases, leading to disrupted sleep and circadian misalignment (i.e., social jet lag). Social factors (e.g., peer influence) and school demands further impact sleep and circadian rhythms. To cope with sleepiness, many teens regularly consume highly caffeinated energy drinks and other stimulants, creating further disruptions in sleep. Chronic sleep loss and circadian misalignment enhance developmental tendencies toward increased reward sensitivity and impulsivity, increasing the likelihood of engaging in risky behaviors and exacerbating the vulnerability to substance use and substance use disorders. We review the neurobiology of brain reward systems and the impact of sleep and circadian rhythms changes on addiction vulnerability in adolescence and suggest areas that warrant additional research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.