Evidence map›Paper›PMID 29372494›Full record

ArticleMolecular biology reports2018

Genetic structure and polymorphism analysis of Xinjiang Hui ethnic minority based on 21 STRs.

Qiong Lan, Jiangang Chen, Yuxin Guo, Tong Xie, Yating Fang, Xiaoye Jin, Wei Cui, Yongsong Zhou, Bofeng Zhu

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Article in Molecular biology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

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11citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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11 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Qiong LanDepartment of Forensic Genetics, School of Forensic Medicine, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China.
Jiangang ChenInstitute of Forensic Science, Ministry of Public Security, Beijing, 100038, People's Republic of China.
Yuxin GuoKey laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, 710004, Shaanxi, People's Republic of China.
Tong XieDepartment of Forensic Genetics, School of Forensic Medicine, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China.
Yating FangDepartment of Forensic Genetics, School of Forensic Medicine, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China.
Xiaoye JinKey laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, 710004, Shaanxi, People's Republic of China.
Wei CuiKey laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, 710004, Shaanxi, People's Republic of China.
Yongsong ZhouDepartment of Forensic Genetics, School of Forensic Medicine, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China.
Bofeng ZhuDepartment of Forensic Genetics, School of Forensic Medicine, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China. zhubofeng7372@126.com.

Funding

National Natural Science Foundation of China 81525015, 81373248
6 · The paper itself

Abstract

In the present study, we calculated the allelic frequencies and forensic descriptive parameters of Hui ethnic minority on the basis of 21 short tandem repeat (STR) loci aiming at understanding population structure better and enriching population genetic database. Bloodstain samples of 506 unrelated healthy Hui individuals in Xinjiang Uygur Autonomous Region were collected. Altogether 268 alleles were observed and the allelic frequencies ranged from 0.0010 to 0.5306. The combined power of discrimination and the cumulative probability of exclusion of the 21 STR loci in Hui ethnic minority were 0.9999999999999999999999998697 and 0.9999999968, respectively. Population data obtained manifested that the panel of 21 STR loci could provide robust genetic information for individual identification and paternity testing involved in forensic applications for Huis of Xinjiang Region. Furthermore, the present results of interpopulation differentiations, phylogenetic trees and principal component analysis which were conducted based on the overlapping 16 STR loci revealed that Hui group was genetically close to Xibe ethnic group and Han populations from different regions.

Indexed as

AllelesAsian PeopleChinaEthnicityFemaleForensic GeneticsGene FrequencyGenetics, PopulationHealthy VolunteersHumansMaleMicrosatellite RepeatsPhylogenyPolymorphism, GeneticPrincipal Component AnalysisSequence Analysis, DNAGlobalFilerHui ethnic minorityPopulation differentiationSTR

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