Evidence map›Paper›PMID 29372451›Full record

ReviewEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2018

Biodentine™ material characteristics and clinical applications: a 3 year literature review and update.

S Rajasekharan, L C Martens, R G E C Cauwels, R P Anthonappa

Erratum issued Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06695208 (Histomorphometric and Radiographic Assessment of Bone After Socket Preservation Using Biodentin Versus Xeno Graft for Socket Preservation of Single Rooted Mandibular Teeth), which is not on this map. Cited by 50 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06695208 phase4recruitingnot on this mapstarted 2024, after this paper: background citation

Histomorphometric and Radiographic Assessment of Bone After Socket Preservation Using Biodentin Versus Xeno Graft for Socket Preservation of Single Rooted Mandibular Teeth: Randomized Clinical Trial

TypeinterventionalSponsorCairo UniversityRan2024 to 2025Enrolled11ConditionsSocket PerservationArmsBiodentine
3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  13. Expert consensus on intentional tooth replantation.International journal of oral science · 2025
    Review
  14. Article
  15. Review
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  18. Prognosis of non-vital incisors after apexification using bioceramics: a retrospective study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

S Rajasekharan *Department of Paediatric Dentistry and special care, PAECOMEDIS Research Cluster, Ghent University, 9000, Ghent, Belgium. sivaprakash.rajasekharan@ugent.be.ORCID http://orcid.org/0000-0003-3075-3356
L C Martens *Department of Paediatric Dentistry and special care, PAECOMEDIS Research Cluster, Ghent University, 9000, Ghent, Belgium.
R G E C Cauwels *Department of Paediatric Dentistry and special care, PAECOMEDIS Research Cluster, Ghent University, 9000, Ghent, Belgium.
R P Anthonappa *Paediatric Oral Health Research Group, School of Dentistry, The University of Western Australia, Perth, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBiodentine™ has frequently been acknowledged in the literature as a promising material and serves as an important representative of tricalcium silicate based cements used in dentistry.

aimTo provide an update on the physical and biological properties of Biodentine™ and to compare these properties with those of other tricalcium silicate cements namely, different variants of mineral trioxide aggregate (MTA) such as ProRoot MTA, MTA Angelus, Micro Mega MTA (MM-MTA), Retro MTA, Ortho MTA, MTA Plus, GCMTA, MTA HP and calcium enriched mixture (CEM), Endosequence and Bioaggregate™. STUDY

designA comprehensive literature search for publications from November 20, 2013 to November 20, 2016 was performed by two independent reviewers on Medline (PubMed), Embase, Web of Science, CENTRAL (Cochrane), SIGLE, SciELO, Scopus, Lilacs and clinicaltrials.gov. Electronic and hand search was carried out to identify randomised control trials (RCTs), case control studies, case series, case reports, as well as in vitro and animal studies published in the English language.

conclusionsThe enhanced physical and biologic properties of Biodentine™ could be attributed to the presence of finer particle size, use of zirconium oxide as radiopacifier, purity of tricalcium silicate, absence of dicalcium silicate, and the addition of calcium chloride and hydrosoluble polymer. Furthermore, as Biodentine™ overcomes the major drawbacks of MTA it has great potential to revolutionise the different treatment modalities in paediatric dentistry and endodontics especially after traumatic injuries. Nevertheless, high quality long-term clinical studies are required to facilitate definitive conclusions.

Indexed as

Aluminum CompoundsAnimalsCalcium CompoundsDental CementsDrug CombinationsHumansOxidesParticle SizePulp Capping and Pulpectomy AgentsSilicatesAluminum CompoundsCalcium CompoundsDental CementsDrug Combinationsmineral trioxide aggregateOxidesPulp Capping and Pulpectomy AgentsSilicatestricalcium silicateBiodentine™Tricalcium silicate

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.