Evidence map›Paper›PMID 29372445›Full record

SynthesisClinical oral investigations2018

Effectiveness of ultrasonically activated irrigation on root canal disinfection: a systematic review of in vitro studies.

Venkateshbabu Nagendrababu, Jayakumar Jayaraman, Anand Suresh, Senthilnayagam Kalyanasundaram, Prasanna Neelakantan

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Clinical oral investigations, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 6 pooled it
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 6 syntheses or guidelines pooled it, 107 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Venkateshbabu NagendrababuDivision of Clinical Dentistry, School of Dentistry, International Medical University, Bukit Jalil, 57000, Kuala Lumpur, Malaysia. venkateshbabu@imu.edu.my.
Jayakumar JayaramanDivision of Children and Community Oral Health, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia.
Anand SureshDepartment of Conservative Dentistry and Endodontics, Penang International Dental College, Jalan Bagan, Laur,12000, Butterworth, Penang, Malaysia.
Senthilnayagam KalyanasundaramDepartment of Dental Surgery, K.A.P.V Government Medical College, Tiruchirappalli, India.
Prasanna NeelakantanDiscipline of Endodontology, Faculty of Dentistry, The University of Hong Kong, Pok Fu Lam, Hong Kong.
International Medical University · MYGovernment Medical College · INRCSI & UCD Malaysia Campus · MYUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesReduction of microbial load from the root canal systems is a pre-requisite for healing of lesions of endodontic origin. Such microbial reduction is influenced by the method of irrigant delivery and activation. The aim of this systematic review was to compare the effect of ultrasonically activated irrigation (UAI) with other irrigation techniques on the reduction of microorganisms during root canal disinfection. MATERIALS AND

methodsThe research question was created based on the PICO strategy. Two reviewers independently performed a comprehensive literature search in electronic databases. Following application of inclusion and exclusion criteria to the selected articles, a systematic data extraction sheet was constructed. The selected articles were assessed using methodological quality scoring protocol. The risk of bias in selected studies was critically assessed by two reviewers.

resultsA total of 15 articles were included for the systematic review. The included studies were heterogeneous in study design; hence, meta-analysis was not performed. The overall risk of bias for the selected studies was moderate. Overall, UAI showed superior reduction of microbial counts, resulting in better disinfection compared to other irrigation systems chosen for comparison in this review.

conclusionThe use of UAI can bring about superior microbial reduction within the root canal system compared to other irrigant activation techniques. CLINICAL RELEVANCE: Activation of irrigants with ultrasonic brings about significant bacterial reduction from the root canal systems compared to other methods of irrigant activation and conventional syringe irrigation. This might help in improving the outcome of root canal treatment.

Indexed as

Dental Pulp CavityDisinfectionHumansIn Vitro TechniquesRoot Canal IrrigantsTherapeutic IrrigationUltrasonicsRoot Canal IrrigantsAntimicrobialColony forming unitsDisinfectionRoot canalUltrasonically activated irrigation

Identifiers

PMID29372445
OpenAlexW2786496311

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.