Evidence map›Paper›PMID 29372409›Full record

ArticleWiener klinische Wochenschrift2018

Do doctors understand the test characteristics of lung cancer screening?

Richard Schmidt, Marie Breyer, Robab Breyer-Kohansal, Matthias Urban, Georg-Christian Funk

Registry-linked trialAbstract read
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In one paragraph

Article in Wiener klinische Wochenschrift, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02542332 (Are Doctors Familiar With the Test Characteristics of Lung Cancer Screening?), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02542332 nacompletednot on this map

Are Doctors Familiar With the Test Characteristics of Lung Cancer Screening?

TypeinterventionalSponsorOtto Wagner HospitalRan2015 to 2015Enrolled556ConditionsInformation About the Knowledge on the Statistical Background of Lung Cancer Screening of DoctorsArmsWith Data
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Effective Educational Approaches to Training Physicians About Lung Cancer Screening.Journal of cancer education : the official journal of the American Association for Cancer Education · 2022
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Richard SchmidtDepartment of Respiratory and Critical Care Medicine, Otto Wagner Hospital, Sanatoriumstr. 2, 1140, Vienna, Austria.
Marie BreyerDepartment of Respiratory and Critical Care Medicine, Otto Wagner Hospital, Sanatoriumstr. 2, 1140, Vienna, Austria.
Robab Breyer-KohansalDepartment of Respiratory and Critical Care Medicine, Otto Wagner Hospital, Sanatoriumstr. 2, 1140, Vienna, Austria.
Matthias UrbanDepartment of Respiratory and Critical Care Medicine, Otto Wagner Hospital, Sanatoriumstr. 2, 1140, Vienna, Austria.
Georg-Christian FunkDepartment of Respiratory and Critical Care Medicine, Otto Wagner Hospital, Sanatoriumstr. 2, 1140, Vienna, Austria. georg-christian.funk@wienkav.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundScreening for lung cancer with a low-dose computed tomography (CT) scan is estimated to prevent 3 deaths per 1000 individuals at high risk; however, false positive results and radiation exposure are relevant harms and deserve careful consideration. Screening candidates can only make an autonomous decision if doctors correctly inform them of the pros and cons of the method; therefore, this study aimed to evaluate whether doctors understand the test characteristics of lung cancer screening.

methodsIn a randomized trial 556 doctors (members of the Austrian Respiratory Society) were invited to answer questions regarding lung cancer screening based on online case vignettes. Half of the participants were randomized to the group 'solutions provided' and received the correct solutions in advance. The group 'solutions withheld' had to rely on prior knowledge or estimates. The primary endpoint was the between-group difference in the estimated number of deaths preventable by screening. Secondary endpoints were the between-group differences in the prevalence of lung cancer, prevalence of a positive screening results, sensitivity, specificity, positive predictive value, and false negative rate. Estimations were also compared with current data from the literature.

resultsThe response rate was 29% in both groups. The reduction in the number of deaths due to screening was overestimated six-fold (95% confidence interval CI: 4-8) compared with the actual data, and there was no effect of group allocation. Providing the correct solutions to doctors had no systematic effect on their answers.

conclusionDoctors poorly understand the test characteristics of lung cancer screening. Providing the correct solutions in advance did not improve the answers. Continuing education regarding lung cancer screening and the interpretation of test characteristics may be a simple remedy. CLINICAL

trial registrationClinical trial registered with www.clinicaltrials.gov (NCT02542332).

Indexed as

Early Detection of CancerLung NeoplasmsMass ScreeningAustriaHumansRandom AllocationTomography, X-Ray ComputedComputed tomographyLung cancerScreeningStatistics

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.