Evidence map›Paper›PMID 29372335›Full record

ArticleJournal of bone and mineral metabolism2019

Higher serum uric acid is associated with higher lumbar spine bone mineral density in male health-screening examinees: a cross-sectional study.

Jiwon Hwang, Jung Hye Hwang, Seungho Ryu, Joong Kyong Ahn

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Article in Journal of bone and mineral metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

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0cells of the map it votes in
15citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Jiwon HwangDepartment of Internal Medicine, National Police Hospital, Seoul, Republic of Korea.
Jung Hye HwangCenter for Health Promotion, Samsung Medical Center, Seoul, Republic of Korea.
Seungho RyuDepartment of Occupational and Environmental Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Samsung Main Building B2, 67 Sejong-daero, Jung-gu, Seoul, 04514, Republic of Korea. sh703.yoo@gmail.com.
Joong Kyong AhnDivision of Rheumatology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-ro, Jongno-gu, Seoul, 03181, Republic of Korea. mdahnjk@skku.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone health has been associated with oxidative stress and antioxidants have received interest to this end. Serum uric acid (SUA), an end product of purine metabolism in humans, has recently shown antioxidant properties regarding bone health, but there are conflicting results. The aim of this study was to investigate the relationship between SUA levels and lumbar spine bone mineral density (BMD) in clinically apparently healthy males aged 40-60 years. We performed a cross-sectional study of 6588 Korean males who completed a health-screening program from January 2011 to December 2014. Of the study participants, the mean age was 48.2 ± 10.7 years. Multiple regression analyses resulted in a significant positive association with lumbar spine BMD across SUA quintiles in a dose-response manner after adjusting for various confounding factors (p = 0.013); for each 1 mg/dl increase of SUA, BMD rose by 0.0054 g/cm

Indexed as

Mass ScreeningAlcoholismAscorbic AcidBody Mass IndexBone DensityCalciumC-Reactive ProteinCross-Sectional StudiesDietExerciseGlomerular Filtration RateHumansInsulin ResistanceLumbar VertebraeMaleMiddle AgedAscorbic AcidCalciumC-Reactive ProteinUric AcidBone healthBone mineral densityDXAMaleUric acid

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.