ArticleNeuroradiology2018
Generalized q-sampling imaging fiber tractography reveals displacement and infiltration of fiber tracts in low-grade gliomas.
Article in Neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Diffusion tensor imaging in detecting gliomas sub-regions of infiltration, local and remote recurrences: a systematic review.Neurosurgical review · 2024Pooled it
- Microstructural alterations of the trigeminal ganglion in chronic ocular surface pain patients: A diffusion MRI study.NeuroImage · 2025Article
- Diffusion tractography of kidney by high angular resolution diffusion imaging.Magnetic resonance letters · 2024Article
- Voxel-Wise Fusion of 3T and 7T Diffusion MRI Data to Extract more Accurate Fiber Orientations.Brain topography · 2024Article
- Qualitative and Visual Along-Tract Analysis of Diffusion-Based Parameters in Patients with Diffuse Gliomas.Brain sciences · 2024Article
- Connectomic insights into the impact of 1p/19q co-deletion in dominant hemisphere insular glioma patients.Frontiers in neuroscience · 2024Article
- Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging-Tractography in Resective Brain Surgery: Lesion Coverage Strategies and Patient Outcomes.Brain sciences · 2023Article
- Intraoperative augmented reality fiber tractography complements cortical and subcortical mapping.World neurosurgery: X · 2023Article
- Review
- Review
- Combined [European radiology · 2022Article
- Preoperative and postoperative high angular resolution diffusion imaging tractography of cerebellar pathways in posterior fossa tumors.Clinical anatomy (New York, N.Y.) · 2022Article
- White Matter Microstructural Alterations in Newly Diagnosed Parkinson's Disease: A Whole-Brain Analysis Using dMRI.Brain sciences · 2022Article
- Association fiber tracts related to Broca's area: A comparative study based on diffusion spectrum imaging and fiber dissection.Frontiers in neuroscience · 2022Article
- Differential Tractography and Correlation Tractography Findings on Patients With Mild Traumatic Brain Injury: A Pilot Study.Frontiers in human neuroscience · 2022Article
- The trajectory of the medial longitudinal fasciculus in the human brain: A diffusion imaging-based tractography study.Human brain mapping · 2021Article
- Review
- Diffusion tractography for awake craniotomy: accuracy and factors affecting specificity.Journal of neuro-oncology · 2021Article
- From Neurosurgical Planning to Histopathological Brain Tumor Characterization: Potentialities of Arcuate Fasciculus Along-Tract Diffusion Tensor Imaging Tractography Measures.Frontiers in neurology · 2021Article
- Tractography and the connectome in neurosurgical treatment of gliomas: the premise, the progress, and the potential.Neurosurgical focus · 2020Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
purposeLow-grade gliomas (LGGs) are slow growing brain tumors that often cause displacement and/or infiltration of the surrounding white matter pathways. Differentiation between infiltration and displacement of fiber tracts remains a challenge. Currently, there is no reliable noninvasive imaging method capable of revealing such white matter alteration patterns. We employed quantitative anisotropy (QA) derived from generalized q-sampling imaging (GQI) to identify patterns of fiber tract alterations by LGGs.
methodsSixteen patients with a neuropathological diagnosis of LGG (WHO grade II) were enrolled. Peritumoral fiber tracts underwent qualitative and quantitative evaluation. Contralateral hemisphere counterparts were used for comparison. Tracts were qualitatively classified as unaffected, displaced, infiltrated or displaced, and infiltrated at once. The average QA of whole tract (W), peritumoral tract segment (S), and their ratio (S/W) were obtained and compared to the healthy side for quantitative evaluation.
resultsQualitative analysis revealed 9 (13.8%) unaffected, 24 (36.9%) displaced, 13 (20%) infiltrated, and 19 (29.2%) tracts with a combination of displacement and infiltration. There were no disrupted tracts. There was a significant increase in S/W ratio among displaced tracts in the pre-operative scans in comparison with the contralateral side. QA values of peritumoral tract segments (S) were significantly lower in infiltrated tracts.
conclusionWHO grade II LGGs might displace, infiltrate, or cause a combination of displacement and infiltration of WM tracts. QA derived from GQI provides valuable information that helps to differentiate infiltration from displacement. Anisotropy changes correlate with qualitative alterations, which may serve as a potential biomarker of fiber tract integrity.
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