ArticleSkeletal radiology2018
Hand MRI and the Greulich-Pyle atlas in skeletal age estimation in adolescents.
Article in Skeletal radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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10 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Magnetic resonance imaging for forensic age estimation in living children and young adults: a systematic review.Pediatric radiology · 2020Pooled it
- Identification of NPR2 gene mutations affecting chondrocyte differentiation in short stature through JAK2-STAT5.Orphanet journal of rare diseases · 2025Article
- Identification and functional analysis of NPR2 truncating mutations in two Chinese families with short stature.BMC pediatrics · 2025Article
- Texture Analysis for the Bone Age Assessment from MRI Images of Adolescent Wrists in Boys.Journal of clinical medicine · 2023Article
- Ultrasound Imaging-Based Methods for Assessing Biological Maturity during Adolescence and Possible Application in Youth Sport: A Scoping Review.Children (Basel, Switzerland) · 2022Article
- Forensic age estimation based on magnetic resonance imaging of the proximal humeral epiphysis in Chinese living individuals.International journal of legal medicine · 2021Article
- Traditional and New Methods of Bone Age Assessment-An OverviewJournal of clinical research in pediatric endocrinology · 2021Article
- Automated Bone Age Assessment Using Artificial Intelligence: The Future of Bone Age Assessment.Korean journal of radiology · 2021Review
- The Use of Age Assessment in the Context of Child Migration: Imprecise, Inaccurate, Inconclusive and Endangers Children's Rights.Children (Basel, Switzerland) · 2019Article
- Forensic age estimation based on T1 SE and VIBE wrist MRI: do a one-fits-all staging technique and age estimation model apply?European radiology · 2019Article
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7 authors at 1 institution in 1 country.
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Abstract
objectiveTo evaluate the feasibility of hand MRI in age assessment in adolescents using the Greulich-Pyle (GP) atlas criteria. MATERIALS AND
methodsTwo radiologists, who were blinded to the study subjects' chronologic ages, semi-objectively evaluated 1.5-T MRIs of the left hands of ten patients (13.5 ± 2.6 years) who had left-hand radiographs and 50 healthy volunteers (15 ± 2 years).
resultsA coronal T1-weighted, volumetric, interpolated, breath-hold examination with water excitation (T1 VIBE-3D-WE) achieved the best image quality. The correlation between estimated patients' ages on radiographs and MRI was high. The average estimated age difference between the MRIs and radiographs was -0.05 years for reader 1 and -0.175 years for reader 2. The interclass coefficients (ICCs) showed high interobserver agreement (radiographs: ICC = 0.95, MRI: ICC = 0.97). The ICC, calculated separately for the male and female volunteers' estimated ages by MRI, also showed a high agreement between the two readers (male: ICC = 0.97, female: ICC = 0.95). Reader 1 estimated 94% of volunteers within 2 standard deviations (SD) and 62% within 1 SD. The results for reader 2 were 92% and 54%, respectively. Thirty-nine percent of girls and 27% of boys were estimated to be older using 1 SD.
conclusionMRI of the left hand is a feasible alternative to hand radiographs for skeletal age estimation in adolescents using the GP criteria with 2 SD. Using 1 SD, the age of healthy volunteers tended to be estimated as higher than the chronologic age. Future studies should evaluate the results in a larger number of participants.
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