ArticleInvestigative ophthalmology & visual science2018
Approach for a Clinically Useful Comprehensive Classification of Vascular and Neural Aspects of Diabetic Retinal Disease.
Article in Investigative ophthalmology & visual science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.
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Who cites it
57 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.
- Risk prediction models for diabetic retinopathy: a systematic review.Frontiers in endocrinology · 2025Pooled it
- Exploring Endotoxemia in Age-Related Macular Degeneration, Glaucoma, and Diabetic Retinopathy.Investigative ophthalmology & visual science · 2026Review
- Review
- Müller cell glutamine metabolism links photoreceptor and endothelial injury in diabetic retinopathy.Life science alliance · 2026Article
- Early Retinal Changes Detected Using Optical Coherence Tomography Angiography in Youth with Type 1 Diabetes Mellitus: A Case-Control Study.Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde · 2026Article
- Article
- Integrative severity scale for diabetic macular atrophy and ischemia using structural OCT and OCT angiography.Scientific reports · 2025Article
- Brief report: harmonic analysis of the 30 Hz flicker ERG in early-stage diabetic retinopathy.Documenta ophthalmologica. Advances in ophthalmology · 2025Article
- Diabetic retinal disease.Nature reviews. Disease primers · 2025Review
- Microvascular changes in eyes with non-proliferative diabetic retinopathy with or without macular microaneurysms: an OCT-angiography study.Acta diabetologica · 2025Article
- Progressive inner retinal neurodegeneration in non-proliferative macular telangiectasia type 2.The British journal of ophthalmology · 2025Article
- Retinal Biomarkers in Diabetic Retinopathy: From Early Detection to Personalized Treatment.Journal of clinical medicine · 2025Review
- Relationship of OCT-Based Diabetic Retinal Neurodegeneration to the Development and Progression of Diabetic Retinopathy: A Cohort Study.Investigative ophthalmology & visual science · 2025Article
- Reduced Aqueous Retinol-Binding Protein 3 Concentration Is Associated With Diabetic Macular Edema and Progression of Diabetic Retinopathy.Diabetes care · 2025Article
- Mitigation of AI adoption bias through an improved autonomous AI system for diabetic retinal disease.NPJ digital medicine · 2024Article
- Development and external validation of a predictive model for type 2 diabetic retinopathy.Scientific reports · 2024Article
- Report From the 2022 Mary Tyler Moore Vision Initiative Diabetic Retinal Disease Clinical Endpoints Workshop.Translational vision science & technology · 2023Article
- Autonomous artificial intelligence increases real-world specialist clinic productivity in a cluster-randomized trial.NPJ digital medicine · 2023Article
- Using Deep Learning Architectures for Detection and Classification of Diabetic Retinopathy.Sensors (Basel, Switzerland) · 2023Article
- Visual Field Abnormalities in Early-Stage Diabetic Retinopathy Assessed by Chromatic Perimetry.Investigative ophthalmology & visual science · 2023Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
The Early Treatment Diabetic Retinopathy Study (ETDRS) and other standardized classification schemes have laid a foundation for tremendous advances in the understanding and management of diabetic retinopathy (DR). However, technological advances in optics and image analysis, especially optical coherence tomography (OCT), OCT angiography (OCTa), and ultra-widefield imaging, as well as new discoveries in diabetic retinal neuropathy (DRN), are exposing the limitations of ETDRS and other classification systems to completely characterize retinal changes in diabetes, which we term diabetic retinal disease (DRD). While it may be most straightforward to add axes to existing classification schemes, as diabetic macular edema (DME) was added as an axis to earlier DR classifications, doing so may make these classifications increasingly complicated and thus clinically intractable. Therefore, we propose future research efforts to develop a new, comprehensive, and clinically useful classification system that will identify multimodal biomarkers to reflect the complex pathophysiology of DRD and accelerate the development of therapies to prevent vision-threatening DRD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.