ArticleActa radiologica open2018
Effects of diffusion time on non-Gaussian diffusion and intravoxel incoherent motion (IVIM) MRI parameters in breast cancer and hepatocellular carcinoma xenograft models.
Article in Acta radiologica open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Diffusion-weighted imaging of the breast-a consensus and mission statement from the EUSOBI International Breast Diffusion-Weighted Imaging working group.European radiology · 2020Guideline
- The Diagnostic Performance of Diffusion Kurtosis Imaging in the Characterization of Breast Tumors: A Meta-Analysis.Frontiers in oncology · 2020Pooled it
- Time-dependent diffusion MRI of soft tissue tumors: correlations with Ki-67 proliferation status.Quantitative imaging in medicine and surgery · 2026Article
- Optimized acquisition for simultaneous intravoxel incoherent motion and RMagnetic resonance in medicine · 2025Article
- Evaluation of Renal Perfusion: A Comparative Study between Intravoxel Incoherent Motion (IVIM) Imaging and Arterial Spin Labeling (ASL) to Assess Renal Blood Flow in Rodents.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025Article
- Influence of Gadolinium-based Contrast Media and Inter-reader Variation on the Estimation of Intravoxel Incoherent Motion (IVIM) Parameters in Breast MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025Article
- In Vivo and Post-mortem Comparisons of IVIM/Time-dependent Diffusion MR Imaging Parameters in Melanoma and Breast Cancer Xenograft Models.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025Article
- Article
- An explanation for the triphasic dependency of apparent diffusion coefficient (ADC) on T2 relaxation time: the multiple T2 compartments model.Quantitative imaging in medicine and surgery · 2025Article
- Single-shot multi-b-value (SSMb) diffusion-weighted MRI using spin echo and stimulated echoes with variable flip angles.NMR in biomedicine · 2024Article
- Reproducibility of intravoxel incoherent motion quantification in the liver across field strengths and gradient hardware.Magnetic resonance in medicine · 2024Article
- Article
- Time-dependent diffusion MRI using multiple stimulated echoes.Magnetic resonance in medicine · 2023Article
- Evaluation of apparent diffusion coefficient of two-dimensional BLADE turbo gradient- and spin-echo diffusion-weighted imaging with a breast phantom.Radiological physics and technology · 2023Article
- Investigation of breast cancer microstructure and microvasculature from time-dependent DWI and CEST in correlation with histological biomarkers.Scientific reports · 2022Article
- Diffusion Breast MRI: Current Standard and Emerging Techniques.Frontiers in oncology · 2022Review
- Diffusion in Sephadex Gel Structures: Time Dependency Revealed by Multi-Sequence Acquisition over a Broad Diffusion Time Range.Mathematics (Basel, Switzerland) · 2021Article
- Intravoxel incoherent motion perfusion in patients with Moyamoya disease: comparison withActa radiologica open · 2019Article
- Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPerfusion-related intravoxel incoherent motion (IVIM) and non-Gaussian diffusion magnetic resonance (MR) parameters are becoming important biomarkers for differentiating malignant from benign tumors without contrast agents. However, diffusion-time dependence has rarely been investigated in tumors. PURPOSE: To investigate the relationship between diffusion time and diffusion parameters in breast cancer and hepatocellular carcinoma xenograft mouse models. MATERIAL AND
methodsDiffusion-weighted MR images (DWI) were obtained on a 7-T magnetic resonance imaging (MRI) scanner at two different diffusion times (9.6 ms and 27.6 ms) in human breast cancer (MDA-MB-231) and hepatocellular carcinoma (HepG2 and PLC/PRF/5) xenograft mouse models. Perfusion-related IVIM (fIVIM and D*) and non-Gaussian diffusion (ADC
resultsADC
conclusionDiffusion MR parameters in both breast cancer and HCC xenograft models were found to be diffusion time-dependent. Our results show that diffusion time is an important parameter to consider when interpreting DWI data.
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