Changes in expression of klotho affect physiological processes, diseases, and cancer.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

1. Association of basal metabolic rate and fuel oxidation in basal conditions and during exercise, with plasma S-klotho: the FIT-AGEING study.Aging · 2019
   Trial
2. Serum klotho levels and mortality patterns in frail individuals: unraveling the u-shaped association.Aging clinical and experimental research · 2024
   Article
3. Metformin: A New Inhibitor of the Wnt Signaling Pathway in Cancer.Cells · 2023
   Article
4. Klotho: A new therapeutic target in diabetic retinopathy?World journal of diabetes · 2023
   Review
5. Association of serum Klotho levels with cancer and cancer mortality: Evidence from National Health and Nutrition Examination Survey.Cancer medicine · 2023
   Article
6. Pan-cancer analyses reveal the immunotherapeutic value of klotho.Heliyon · 2022
   Article
7. Prognostic Value of Serum Soluble Klotho and Fibroblast Growth Factor-23 in Multiple Myeloma Patients.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2022
   Article
8. Undetected αKlotho in serum is associated with the most aggressive phenotype of breast cancer.Molecular and clinical oncology · 2022
   Article
9. Enhancement of Apo2L/TRAIL signaling pathway receptors by the activation of Klotho gene with CRISPR/Cas9 in Caco-2 colon cancer cells.Medical oncology (Northwood, London, England) · 2021
   Article
10. Klotho Inhibits Proliferation in a RET Fusion Model of Papillary Thyroid Cancer by Regulating the Wnt/β-Catenin Pathway.Cancer management and research · 2021
    Article
11. Serum Klotho levels in primary hyperparathyroidism patients before and after parathyroidectomy.Endocrine · 2020
    Article
12. TRPV6 as A Target for Cancer Therapy.Journal of Cancer · 2020
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

2 authors at 1 institution in 2 countries.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as