Evidence map›Paper›PMID 29371938›Full record

ArticleOncotarget2017

Large-scale copy number analysis reveals variations in genes not previously associated with malignant pleural mesothelioma.

Marieke Hylebos, Guy Van Camp, Geert Vandeweyer, Erik Fransen, Matthias Beyens, Robin Cornelissen, Arvid Suls, Patrick Pauwels, Jan P van Meerbeeck, Ken Op de Beeck

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Genomics and Functional Genomics of Malignant Pleural Mesothelioma.International journal of molecular sciences · 2020
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Marieke HylebosCenter of Medical Genetics, University of Antwerp and Antwerp University Hospital, 2650 Antwerp, Belgium.
Guy Van CampCenter of Medical Genetics, University of Antwerp and Antwerp University Hospital, 2650 Antwerp, Belgium.
Geert VandeweyerCenter of Medical Genetics, University of Antwerp and Antwerp University Hospital, 2650 Antwerp, Belgium.
Erik FransenCenter of Medical Genetics, University of Antwerp and Antwerp University Hospital, 2650 Antwerp, Belgium.
Matthias BeyensCenter of Medical Genetics, University of Antwerp and Antwerp University Hospital, 2650 Antwerp, Belgium.
Robin CornelissenDepartment of Pulmonary Medicine, Erasmus Medical Center Cancer Institute, 3015 Rotterdam, The Netherlands.
Arvid SulsCenter of Medical Genetics, University of Antwerp and Antwerp University Hospital, 2650 Antwerp, Belgium.
Patrick PauwelsCenter for Oncological Research, University of Antwerp, 2610 Antwerp, Belgium.
Jan P van MeerbeeckCenter for Oncological Research, University of Antwerp, 2610 Antwerp, Belgium.
Ken Op de BeeckCenter of Medical Genetics, University of Antwerp and Antwerp University Hospital, 2650 Antwerp, Belgium.
Antwerp University Hospital · BEUniversity of Antwerp · BEErasmus MC Cancer Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant pleural mesothelioma (MPM) is an aggressive tumor that is often causally associated with asbestos exposure. Comparative genomic hybridization techniques and arrays demonstrated a complex set of copy number variations (CNVs) in the MPM-genome. These techniques however have a limited resolution, throughput and flexibility compared to next-generation sequencing platforms. In this study, the presence of CNVs in the MPM-genome was investigated using an MPM-cohort (

Indexed as

cancer census genescopy number variationslow-pass whole genome sequencingmalignant pleural mesotheliomathe cancer genome atlas

Identifiers

PMID29371938
PMCPMC5768355
OpenAlexW2772260485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.