Evidence map›Paper›PMID 29371929›Full record

ArticleOncotarget2017

miR-769-5p suppressed cell proliferation, migration and invasion by targeting TGFBR1 in non-small cell lung carcinoma.

Zhao Yang, Jin He, Peng Gao, Yi Niu, Jie Zhang, Lei Wang, Meiyue Liu, Xiaomei Wei, Chunling Liu, Chao Zhang and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. World journal of gastroenterology · 2025
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  20. Suppression of Circular RNA Hsa_circ_0109320 Attenuates Non-Small Cell Lung Cancer Progression via MiR-595/E2F7 Axis.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Zhao YangDepartment of Radiation Oncology, North China University of Science and Technology Affiliated People's Hospital, Tangshan, China.
Jin HeDepartment of Hepatobiliary Tumor, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Cencer, Tianjin, China.
Peng GaoDepartment of Radiation Oncology, North China University of Science and Technology Affiliated People's Hospital, Tangshan, China.
Yi NiuDepartment of Radiation Oncology, North China University of Science and Technology Affiliated People's Hospital, Tangshan, China.
Jie ZhangDepartment of Pathology, North China University of Science and Technology Affiliated People's Hospital, Tangshan, China.
Lei WangDepartment of Pathology, North China University of Science and Technology Affiliated People's Hospital, Tangshan, China.
Meiyue LiuDepartment of Radiation Oncology, North China University of Science and Technology Affiliated People's Hospital, Tangshan, China.
Xiaomei WeiDepartment of Radiation Oncology, North China University of Science and Technology Affiliated People's Hospital, Tangshan, China.
Chunling LiuDepartment of Pathology, North China University of Science and Technology Affiliated People's Hospital, Tangshan, China.
Chao ZhangDepartment of Radiation Oncology, North China University of Science and Technology Affiliated People's Hospital, Tangshan, China.
Wei WangDepartment of Radiation Oncology, North China University of Science and Technology Affiliated People's Hospital, Tangshan, China.
Jiayi DuDepartment of Pathology, North China University of Science and Technology Affiliated People's Hospital, Tangshan, China.
Hongmin LiDepartment of Pathology, North China University of Science and Technology Affiliated People's Hospital, Tangshan, China.
Wanning HuDepartment of Radiation Oncology, North China University of Science and Technology Affiliated People's Hospital, Tangshan, China.
Guogui SunDepartment of Radiation Oncology, North China University of Science and Technology Affiliated People's Hospital, Tangshan, China.
North China University of Science and Technology · CNTianjin Medical University Cancer Institute and Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) are key regulators of multiple cancers, including non-small cell lung carcinoma (NSCLC). The aim of this study was to determine the expression pattern of miR-769-5p in NSCLC and to investigate its biological role during tumorigenesis. We showed that miR-769-5p was significantly downregulated and predicted poor prognosis in NSCLC compared with corresponding normal tissues. We then investigated its function and found that miR-769-5p significantly inhibited cell proliferation, migration and invasion

Indexed as

gene therapyinvasion and metastasislung cancermicroRNAs

Identifiers

PMID29371929
PMCPMC5768346
OpenAlexW2775401927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.